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Pocket Companion to Robbins & Cotran Pathologic Basis of Disease, 10th Edition

Richard Mitchell, Abul K. Abbas, Jon C. Aster, Vinay Kumar
ISBN: 9780323653909
ISBN: 9780323653909
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Διαστάσεις 21 × 10 cm
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Original price was: 42,00€.Η τρέχουσα τιμή είναι: 37,00€.(Περιλαμβάνεται ΦΠΑ 6%)

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Περιγραφή

Offering rapid, portable access to key concepts and principles of pathology from Robbins and Cotran Pathologic Basis of Disease, 10th Edition, this up-to-date Pocket Companion makes it easy to locate essential information on the go. The condensed, at-a-glance format, organized to parallel the parent text, is ideal for quick review—anytime, anywhere.
Key Features
  • Features cutting-edge information on important topics such as novel therapies for hepatitis C, personalized medicine, the role of microbiome and metabolome in non-communicable disease, and much more.
  • Includes new gross and microscopic figures for clarity of morphology and new artwork depicting the latest advances in molecular pathogenesis of cancers.
  • Reflects updated page references and content changes found in to Robbins and Cotran Pathologic Basis of Disease, 10th Edition.
  • Contains all the key data and principles needed for the USMLE Step 1, in-course exams, and rotations.
  • Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Περιεχόμενα

  • Cover image
  • Title page
  • Table of Contents
  • Copyright
  • Contributors
  • Preface
  • General Pathology
  • 1. The Cell as a Unit of Health and Disease
  • The Genome (p. 1)
  • Cellular Housekeeping (p. 6)
  • Cellular Metabolism and Mitochondrial Function (p. 15)
  • Cellular Activation (p. 16)
  • Signal Transduction Pathways (p. 17)
  • Growth Factors and Receptors (p. 20)
  • Extracellular Matrix (p. 21)
  • Maintaining Cell Populations (p. 25)
  • 2. Cell Injury, Cell Death, and Adaptations
  • Introduction to Pathology (p. 33)
  • Overview of Cellular Responses to Stress and Noxious Stimuli (p. 34)
  • Causes of Cell Injury (p. 36)
  • The Progression of Cell Injury and Death (p. 36)
  • Necrosis (p. 39)
  • Apoptosis (p. 42)
  • Other Mechanisms of Cell Death (p. 47)
  • Mechanisms of Cell Injury (p. 49)
  • Examples of Cell Injury and Death (p. 55)
  • Adaptations of Cellular Growth and Differentiation (p. 57)
  • Intracellular Accumulations (p. 62) (Fig. 2.18)
  • Pathologic Calcification (p. 65)
  • Cellular Aging (p. 66)
  • 3. Inflammation and Repair
  • Overview of Inflammation: Definitions and General Features (p. 71)
  • Acute Inflammation (p. 75)
  • Mediators of Inflammation (p. 85)
  • Morphologic Patterns of Acute Inflammation (p. 93)
  • Outcomes of Acute Inflammation (p. 95; Fig. 3.11)
  • Summary of Acute Inflammation (p. 95)
  • Chronic Inflammation (p. 96)
  • Systemic Effects of Inflammation (p. 101)
  • Tissue Repair (p. 103)
  • 4. Hemodynamic Disorders, Thromboembolic Disease, and Shock
  • Edema and Effusions (p. 115)
  • Hyperemia and Congestion (p. 117)
  • Hemostasis, Hemorrhagic Disorders, and Thrombosis (p. 118)
  • Embolism (p. 130)
  • Infarction (p. 133)
  • Shock (p. 134)
  • 5. Genetic Disorders
  • Genes and Human Diseases (p. 141)
  • Mendelian Disorders (p. 144)
  • Complex Multigenic Disorders (p. 163)
  • Chromosomal Disorders (p. 164)
  • Single-Gene Disorders With Nonclassic Inheritance (p. 173)
  • Molecular Genetic Diagnosis (p. 180)
  • 6. Diseases of the Immune System
  • The Normal Immune Response (p. 190)
  • Hypersensitivity: Immunologically Mediated Tissue Injury (p. 204)
  • Rejection of Tissue Transplants (p. 234)
  • Immunodeficiency Diseases (p. 240)
  • Amyloidosis (p. 259)
  • 7. Neoplasia
  • Nomenclature (p. 268)
  • Characteristics of Benign and Malignant Neoplasms (p. 270)
  • Epidemiology of Cancer (p. 277)
  • Molecular Basis of Cancer: Role of Genetic and Epigenetic Alterations (p. 281)
  • Molecular Basis of Multistep Carcinogenesis (p. 320)
  • Carcinogenic Agents and Their Cellular Interactions (p. 320)
  • Clinical Aspects of Neoplasia (p. 328)
  • 8. Infectious Diseases
  • General Principles of Microbial Pathognesis (p. 399)
  • Viral Infections (p. 349; Table 8.4)
  • Bacterial Infections (p. 359; Table 8.5)
  • Fungal Infections (p. 383)
  • Parasitic Infections (p. 388; Table 8.6)
  • Sexually Transmitted Infections (STIs; p. 399; see also Chapters 21 and 22)
  • Special Techniques for Diagnosing Infectious Agents (p. 401)
  • 9. Environmental and Nutritional Diseases
  • Health Effects of Climate Change (p. 406)
  • Toxicity of Chemical and Physical Agents (p. 407)
  • Environmental Pollution (p. 408)
  • Occupational Health Risks: Industrial and Agricultural Exposures (p. 414)
  • Effects of Tobacco (p. 415)
  • Effects of Alcohol (p. 418)
  • Injury by Therapeutic Drugs and Drugs of Abuse (p. 420)
  • Injury by Physical Agents (p. 426)
  • Nutritional Diseases (p. 433)
  • 10. Diseases of Infancy and Childhood
  • Congenital Anomalies (p. 453)
  • Prematurity and Fetal Growth Restriction (p. 457)
  • Perinatal Infections (p. 461)
  • Fetal Hydrops (p. 462)
  • Inborn Errors of Metabolism and Other Genetic Disorders (p. 464)
  • Sudden Infant Death Syndrome (SIDS; p. 473)
  • Tumors and Tumorlike Lesions of Infancy and Childhood (p. 475)
  • Systemic Pathology: Diseases of Organ Systems
  • 11. Blood Vessels
  • Vascular Structure and Function (p. 485)
  • Vascular Anomalies (p. 487)
  • Vascular Wall Response to Injury (p. 487)
  • Hypertensive Vascular Disease (p. 489)
  • Arteriosclerosis (p. 493)
  • Atherosclerosis (p. 493)
  • Aneurysms and Dissection (p. 504)
  • Vasculitis (p. 508)
  • Antiendothelial Cell Antibodies (p. 511)
  • Disorders of Blood Vessel Hyper-Reactivity (p. 516)
  • Veins (p. 517)
  • Vascular Tumors (p. 518)
  • Pathology of Vascular Intervention (p. 523)
  • 12. The Heart
  • Cardiac Structure and Specializations (p. 527)
  • Effects of Aging on the Heart (p. 528)
  • Overview of Cardiac Pathophysiology (p. 529)
  • Heart Failure (p. 530)
  • Cardiac Development (p. 534)
  • Congenital Heart Disease (CHD; p. 534)
  • Ischemic Heart Disease (p. 542)
  • Arrhythmias (p. 554)
  • Hypertensive Heart Disease (p. 555)
  • Valvular Heart Disease (p. 557)
  • Cardiomyopathies (p. 567)
  • Pericardial Disease (p. 577)
  • Tumors of the Heart (p. 579)
  • Cardiac Transplantation (p. 580)
  • Cardiac Devices (p. 580)
  • 13. Diseases of White Blood Cells, Lymph Nodes, Spleen, and Thymus
  • Normal Hematopoiesis (p. 584)
  • Disorders of White Cells (p. 586)
  • Leukopenia (p. 586)
  • Reactive Proliferations of White Cells and Lymph Nodes (p. 587)
  • Neoplastic Proliferations of White Cells (p. 590)
  • Spleen (p. 628)
  • Thymus (p. 631; see also Chapter 6)
  • 14. Red Blood Cell and Bleeding Disorders
  • Anemias (p. 635)
  • Polycythemia (p. 662)
  • Bleeding Disorders: Hemorrhagic Diatheses (p. 662)
  • 15. The Lung
  • Congenital Anomalies (p. 674)
  • Atelectasis (Collapse) (p. 674)
  • Pulmonary Edema (p. 675)
  • Acute Lung Injury and Acute Respiratory Distress Syndrome (Diffuse Alveolar Damage) (p. 676)
  • Obstructive and Restrictive Lung Diseases (p. 678)
  • Obstructive Lung Diseases (p. 678)
  • Chronic Diffuse Interstitial (Restrictive) Diseases (p. 688)
  • Diseases of Vascular Origin (p. 700)
  • Lung Transplantation (p. 714)
  • Tumors (p. 715)
  • 16. Head and Neck
  • Oral Cavity (p. 731)
  • Upper Airways (p. 739)
  • Neck p. 745)
  • Salivary Glands (p. 747)
  • 17. The Gastrointestinal Tract
  • Congenital Abnormalities (p. 754)
  • Diaphragmatic Hernia, Omphalocele, and Gastroschisis (p. 754)
  • Ectopia (p. 755)
  • Pyloric Stenosis (p. 755)
  • Hirschsprung Disease (p. 755)
  • Esophagus (p. 757)
  • Achalasia (p. 757)
  • Esophagitis and Related Disorders (p. 758)
  • Barrett Esophagus (p. 761)
  • Esophageal Tumors (p. 762)
  • Stomach (p. 764)
  • Chronic Gastritis and Its Complications (p. 766)
  • Other Complications of Chronic Gastritis
  • Hypertrophic Gastropathies (p. 771; Table 17.1)
  • Gastric Polyps and Tumors (p. 773; Table 17.1)
  • Small Intestine and Colon (p. 780)
  • Intestinal Obstruction (p. 780)
  • Ischemic Bowel Disease (p. 781)
  • Angiodysplasia (p. 783)
  • Malabsorption and Diarrhea (p. 783)
  • Infectious Enterocolitis (p. 787)
  • Irritable Bowel Syndrome (IBS; p. 798)
  • Inflammatory Bowel Disease (IBD; p. 798)
  • Other Causes of Chronic Colitis (p. 805)
  • Graft-Versus-Host Disease (GVHD; p. 805)
  • Sigmoid Diverticular Disease (p. 806)
  • Polyps (p. 807)
  • Adenocarcinoma (p. 813)
  • Hemorrhoids (p. 818)
  • Acute Appendicitis (p. 818)
  • Tumors of the Appendix (p. 819)
  • Peritoneal Cavity (p. 820)
  • Tumors (p. 820)
  • 18. Liver and Gallbladder
  • The Liver and Bile Ducts (p. 823)
  • Infectious Disorders (p. 831)
  • Autoimmune Hepatitis (AIH; p. 839)
  • Drug- and Toxin-Induced Liver Injury (p. 841)
  • Fatty Liver Disease (p. 842)
  • Inherited Liver Disease (p. 848)
  • Autoimmune Cholangiopathies (p. 857)
  • Circulatory Disorders (p. 861; Fig. 18.10)
  • Hepatic Disease Associated With Pregnancy (p. 864)
  • Nodules and Tumors (p. 865)
  • Gallbladder (p. 872)
  • 19. The Pancreas
  • Congenital Anomalies (p. 881)
  • Pancreatitis (p. 882)
  • Non-Neoplastic Cysts (p. 888)
  • Neoplasms (p. 886)
  • 20. The Kidney
  • Clinical Manifestations of Renal Diseases (p. 896)
  • Glomerular Diseases (p. 897)
  • Tubular and Interstitial Diseases (p. 924)
  • Vascular Diseases (p. 935)
  • Congenital and Developmental Anomalies (p. 940)
  • Cystic Diseases of the Kidney (p. 941)
  • Urolithiasis (Renal Calculi, Stones) (p. 947)
  • Neoplasms of the Kidney (p. 948)
  • 21. The Lower Urinary Tract and Male Genital System
  • The Lower Urinary Tract (p. 953)
  • Urinary Bladder (p. 955)
  • Urethra (p. 963)
  • The Male Genital Tract (p. 963)
  • Prostate (p. 975)
  • 22. The Female Genital Tract
  • Infections (p. 986)
  • Vulva (p. 989)
  • Vagina (p. 994)
  • Cervix (p. 995)
  • Body of Uterus and Endometrium (p. 1001)
  • Fallopian Tubes (p. 1015)
  • Ovaries (p. 1016)
  • Gestational and Placental Disorders (p. 1028)
  • 23. The Breast
  • Disorders of Development (p. 1038)
  • Clinical Presentation of Breast Disease (p. 1038)
  • Inflammatory Disorders (p. 1040)
  • Benign Epithelial Lesions (p. 1042)
  • Carcinoma of the Breast (p. 1046)
  • Types of Breast Carcinoma (p. 1053)
  • 24. The Endocrine System
  • Pituitary Gland (p. 1066)
  • Thyroid Gland (p. 1075)
  • Parathyroid Glands (p. 1093)
  • The Endocrine Pancreas (p. 1097)
  • Adrenal Glands (p. 1114)
  • Pineal Gland (p. 1130)
  • 25. The Skin
  • The Skin: More Than a Mechanical Barrier (p. 1133)
  • Disorders of Pigmentation and Melanocytes (p. 1135)
  • Benign Epithelial Tumors (p. 1102)
  • Premalignant and Malignant Epidermal Tumors (p. 1145)
  • Tumors of the Dermis (p. 1149)
  • Tumors of Cellular Migrants to the Skin (p. 1151)
  • Disorders of Epidermal Maturation (p. 1152)
  • Acute Inflammatory Dermatoses (p. 1153)
  • Chronic Inflammatory Dermatoses (p. 1157)
  • Blistering (Bullous) Diseases (p. 1159)
  • Disorders of Epidermal Appendages (p. 1165)
  • Panniculitis (p. 1166)
  • Infection (p. 1166)
  • 26. Bones, Joints, and Soft Tissue Tumors
  • Bones (p. 1171)
  • Joints (p. 1197)
  • Soft Tissue Tumors (p. 1208)
  • 27. Peripheral Nerves and Skeletal Muscles
  • Diseases of Peripheral Nerves (p. 1217)
  • Specific Peripheral Neuropathies (p. 1220)
  • Diseases of the Neuromuscular Junction (p. 1225)
  • Diseases of Skeletal Muscle (p. 1227)
  • Peripheral Nerve Sheath Tumors (p. 1236)
  • 28. The Central Nervous System
  • Cellular Pathology of the Central Nervous System (p. 1242)
  • Cerebral Edema, Hydrocephalus, Raised Intracranial Pressure, and Herniation (p. 1244)
  • Malformations and Developmental Disorders (p. 1245)
  • Perinatal Brain Injury (p. 1248)
  • Trauma (p. 1249)
  • Cerebrovascular Disease (p. 1253)
  • Infections (p. 1261)
  • Demyelinating Diseases (p. 1269)
  • Neurodegenerative Diseases (p. 1273)
  • Genetic Metabolic Diseases (p. 1289)
  • Toxic and Acquired Metabolic Diseases (p. 1291)
  • Tumors (p. 1293)
  • 29. The Eye
  • Orbit (p. 1306)
  • Eyelid (p. 1307)
  • Conjunctiva (p. 1308)
  • Sclera (p. 1310)
  • Cornea (p. 1310)
  • Anterior Segment (p. 1313)
  • Uvea (p. 1315)
  • Retina and Vitreous (p. 1318)
  • Optic Nerve (p. 1325)
  • The End-Stage Eye: Phthisis Bulbi (p. 1328)
  • Index

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