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Diffusion MRI of the Breast, 1st Edition

ISBN: 9780323797023
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Περιγραφή

Diffusion weighted imaging (DWI) is a key emerging imaging modality for the management of patients with possible breast lesions, and Diffusion MRI of the Breast is the first book to focus on all aspects of DWI in today’s practice. It covers the knowledge necessary to undertake clinical breast DWI, with a thorough review of how DWI is currently used as a breast imaging modality and how breast lesions appear on DWI. Expert clinicians and physicists from around the world share their knowledge and expertise on everything from technical requirements and image analysis to clinical applications of DWI (diagnosis, prognosis, treatment monitoring) with case examples, and upcoming developments in the field (radiomics, AI).
Key Features
  • Offers an in-depth discussion of DWI’s clinical applications in breast imaging, including the position of DWI with respect to other modalities, the use of DWI in the diagnosis of suspicious lesions with a multiparametric protocol, the use of DWI as an imaging biomarker of prognosis and response prediction, the potential role of DWI for unenhanced breast MR screening, and more.
  • Provides a basic introduction to DWI before discussing a practical approach to clinical interpretation and quality assurance issues.
  • Covers specific challenges and advanced techniques (IVIM, non-Gaussian diffusion, DTI, and other novel techniques), radiomics and artificial intelligence, and different vendor approaches in breast DWI packages.
  • Features more than 500 high-quality images throughout.
  • Explains how DWI could be specifically used to provide information on prognosis and prediction factors.
  • Evaluates the current status of DWI, its potential for the management of breast cancer patients, and possible future developments in the field.
  • Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Author Information
Edited by Mami Iima; Savannah Partridge, Professor, Department of Radiology, University of Washington, Seattle, WA, USA and Denis Le Bihan

Περιεχόμενα

Cover image
Title page
Table of Contents
Any screen, Any time, Anywhere
Copyright
List of Contributors
Foreword
Chapter 1. General Principles and Challenges of Diffusion MRI
Abstract
Basic Diffusion MRI, Diffusion-Weighted Imaging (DWI), and the Classic Apparent Diffusion Coefficient (ADC)
Pitfalls, Challenges, and Common Issues Found in Clinical Practice
Conclusion
References
Chapter 2. Conventional Breast Imaging
Abstract
Imaging Techniques and Image-Guided Biopsy
Using Conventional Breast Imaging in Clinical Practice
DWI of the Breast
References
Chapter 3. Overview of Breast DWI: Diagnosis of Suspicious Lesions Using DWI in Combination With Standard MRI
Abstract
The Need for Reducing Unnecessary Biopsies in Breast MRI
DWI and the ADC in Clinical Practice
Analysis of DWI Images
Considerations for Implementing ADC Measurements in Clinical Practice
Future Considerations
References
Chapter 4. Biomarkers, Prognosis, and Prediction Factors
Abstract
Background
Classification of Breast Cancer
Diffusion-Weighted Imaging Predicting Markers of Tumor Aggressiveness
Diffusion-Weighted Imaging for Tumor Staging and Surgical Planning
Future Directions
Conclusions
References
Chapter 5. Disease and Treatment Monitoring
Abstract
Diffusion-Weighted Magnetic Resonance Imaging Approaches for Treatment Monitoring
Tumor Mean ADC for Predicting Response
Alternative DWI Metrics to Mean ADC
Combined DCE and DWI Approaches to Outcome Prediction
Subtype Dependency of ADC Prediction
Current Challenges and Future Directions
References
Chapter 6. Diffusion MRI as a Stand-Alone Unenhanced Approach for Breast Imaging and Screening
Abstract
List of Abbreviations
Current Evidence for DW MRI as a Stand-Alone Modality
Technical Requirements as an Unenhanced Screening Modality
Image Interpretation Strategies
Target Population for Unenhanced MRI Screening
Other Issues in Clinical Implementation
Ongoing Prospective Trials
Summary
References
Chapter 7. DWI and Breast Physiology Status
Abstract
Menstrual Cycle
Pregnancy and Lactation
Involution
Pregnancy-Associated Breast Cancer
Menopause
Summary and Outlook
References
Chapter 8. IVIM and Non-Gaussian DWI of the Breast
Abstract
Intravoxel Incoherent Motion and Non-Gaussian Diffusion-Weighted Imaging: Introduction
Clinical Application of IVIM and Non-Gaussian DWI
Image Acquisition Schemes for Breast DWI
Data Analysis of IVIM and Non-Gaussian DWI
Balancing Biophysical Complexity and Practical Clinical Benefit
References
Chapter 9. Diffusion Tensor Imaging (DTI) of the Breast
Abstract
DTI in the Breast: Basics, Metrics, and Pitfalls
Fibroglandular Tissue (FGT) DTI
Clinical Application of Breast DTI
Breast DTI: Advances and Extensions
Overview/Outlook
References
Chapter 10. Artificial Intelligence—Enhanced Breast MRI and DWI: Current Status and Future Applications
Abstract
Background
Basic Concepts of Radiomics and AI Methodology
AI-Enhanced Breast MRI
Use Cases
Challenges and Future Perspectives
Conclusion
References
Chapter 11. Diffusion-Weighted Whole Body Imaging With Background Body Signal Suppression (DWIBS)
Abstract
Basic Concept of Diffusion-Weighted Whole Body Imaging With Background Body Signal Suppression (DWIBS)
The Importance of Fat Suppression in DWIBS
Application to Breast Cancer Screening
Limitations of DWIBS
References
Chapter 12. High-Resolution Diffusion-Weighted Breast MRI Acquisition
Abstract
Standard Echo-Planar Diffusion-Weighted Imaging
Fat-Suppression Methods
Reducing Distortion, Blurring, and Scan Times With Available Methods
Other Advanced Methods
Summary
References
Chapter 13. Clinical Interpretation of Diffusion MRI, ROI Assessment, Common Errors, Pitfalls and Artifacts, Challenges in Acquisition
Abstract
Clinical Interpretation
REGION OF INTEREST (ROI) ASSESSMENT
Common Errors, Pitfalls, Artifacts
Challenges in Acquisition
References
Chapter 14. Multiplatform Standardization of Breast DWI Protocols: Quality Control and Test Objects
Abstract
Overview of Breast Diffusion-Weighted Imaging Standardization Efforts
Optimization and Standardization of Breast DWI Acquisition and Analysis
Test Objects and Quality Control for Breast DWI
Conclusion
References
Chapter 15. Routine and Advanced Breast DWI Techniques and Processing: The Siemens Healthineers Per spective
Abstract
Data Acquisition
Data Processing and Management
Works in Progress
References
Chapter 16. Breast Diffusion MRI Acquisition and Processing Techniques: The GE Healthcare Perspective
Abstract
Data Acquisition
Data Processing and Reconstruction
References
Chapter 17. Breast DWI Techniques and Processing: The Philips Perspective
Abstract
Data Acquisition
Essential Elements of Postprocessing
Future Aspects
References
Chapter 18. Diffusion-Weighted Imaging (DWI) for Breast Lesion Characterization: The Olea Medical Perspective and the Utilization of Olea Sphere Software
Abstract
The Importance of Postprocessing and Data Analysis for Breast Diffusion Weighted Imaging
Breast Diffusion Image Pre- and Postprocessing in Olea Sphere
Future Directions
Acknowledgments
References
Index
Confidence is ClinicalKey