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Rau’s Respiratory Care Pharmacology, 11th Edition

ISBN: 9780323871556
ISBN: 9780323871556
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Διαθέσιμο - Προπαραγγελία|Διαθεσιμότητα: 11-14 ημέρες

Περιγραφή

You can breathe a little easier knowing there’s a proven way to master respiratory pharmacology! For more than 30 years, Rau’s Respiratory Care Pharmacology has been the preeminent text on the subject. With easy-to-grasp terminology, relatable explanations, and reader-friendly writing, it simplifies the process of learning pharmacology material like never before. Rau’s is organized into three logical sections, covering the basics of respiratory care, frequently used drugs, and critical care medications. New to the 11th edition are recently approved FDA drugs, information on drug approvals, COVID-19 coverage, and new and updated Clinical Connection boxes that focus on important clinical questions, assisting you in connecting the information in the text to the clinical setting and addressing how Respiratory Therapists can help educate patients.

New to this edition

NEW and UPDATED! Clinical Connection boxes assist you in connecting information in the text to the clinical setting, including providing patients a better understanding of their clinical conditions as related to their drug treatments.
UPDATED! Chapter 1 reflects changes to drug approval.
UPDATED! Chapter 3 reflects changes in aerosol medication devices and addresses aerosol-generating device issues and COVID-19.
UPDATED! The latest FDA-approved medications are referenced in all chapters.
UPDATED! Current asthma (GINA) and COPD (GOLD) guidelines include COVID-19 treatment protocols.
Enhanced readability helps you more easily understand difficult material.

Key Features

Clinical scenarios with follow-up SOAP assessment help you assess your comprehension of the material.
Self-assessment questions offer you thought-provoking opportunities to test your comprehension of key concepts.
Learning objectives parallel the levels tested by the NBRC® exams to help you identify important information that goes beyond memorization and recall.
Key terms with definitions provide easy access to the pharmacologic vocabulary you should embrace.
Key points boxes in each chapter highlight important concepts in the lesson.
Glossary of all key terms in the text aids you in understanding the terminology associated with respiratory care pharmacology.
Appendices on common Units and Systems of Measurement and Acceptable Mixtures provide references to need-to-know information such as abbreviations, conversion charts for temperatures, liquid metric and solids, and a simple drug compatibility chart for drug mixtures.
Alphabetical drug index provides a direct index to look up information based on drug name.

Author Information
By Douglas S. Gardenhire, EdD, RRT-NPS, FAARC, Chair and Clinical Associate Professor, Department of Respiratory Therapy, Lewis School of Nursing and Health Professions, Georgia State University, Atlanta, Georgia

Περιεχόμενα

  • Cover Image
  • Title Page
  • Copyright
  • Dedication
  • Contributors
  • Preface
  • Acknowledgments
  • Table of Contents
  • Unit A Basic Concepts and Principles in Pharmacology
  • Chapter 1 Introduction to Respiratory Care Pharmacology
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Pharmacology and the Study of Drugs
  • Naming Drugs
  • Sources of Drug Information
  • Sources of Drugs
  • Process for Drug Approval in the United States
  • The Prescription
  • Respiratory Care Pharmacology: An Overview
  • References
  • Chapter 2 Principles of Drug Action
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Drug Administration Phase
  • Pharmacokinetic Phase
  • Pharmacodynamic Phase
  • Pharmacogenetics
  • References
  • Chapter 3 Administration of Aerosolized Agents
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Physical Principles of Inhaled Aerosol Drugs
  • Aerosol Generators for Drug Delivery
  • Selecting an Aerosol Device
  • Clinical Application of Aerosol Delivery Devices
  • References
  • Chapter 4 Calculating Drug Doses
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Systems of Measure
  • Calculating Doses From Prepared-Strength Solutions
  • Calculating Doses From Percent-Strength Solutions
  • Reference
  • Chapter 5 Central and Peripheral Nervous Systems
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Nervous System
  • Autonomic Branches
  • Parasympathetic Branch
  • Cholinergic Agents
  • Anticholinergic Agents
  • Sympathetic Branch
  • Sympathomimetic (Adrenergic) and Sympatholytic (Antiadrenergic) Agents
  • Neural Control of Lung Function
  • References
  • Unit B Drugs Used to Treat the Respiratory System
  • Chapter 6 Adrenergic (Sympathomimetic) Bronchodilators
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Clinical Indications for Adrenergic Bronchodilators
  • Specific Adrenergic Agents and Formulations
  • Levalbuterol: (R)-Isomer of Albuterol
  • Long-Acting β-Adrenergic Agents
  • Mechanism of Action
  • Routes of Administration
  • Oral Route
  • Parenteral Route
  • Adverse Side Effects
  • Compatibility of Other Agents With Bronchodilators
  • β-Agonist Controversy
  • Respiratory Care Assessment of β-Agonist Therapy
  • References
  • Chapter 7 Anticholinergic (Parasympatholytic) Bronchodilators
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Clinical Indications for Use
  • Specific Anticholinergic (Parasympatholytic) Agents
  • Clinical Pharmacology
  • Mechanism of Action
  • Adverse Effects
  • Clinical Application
  • Respiratory Care Assessment of Anticholinergic Bronchodilator Therapy
  • References
  • Chapter 8 Xanthines
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Clinical Indications for the Use of Xanthines
  • Specific Xanthine Agents
  • General Pharmacologic Properties
  • Titrating Theophylline Doses
  • Respiratory Care Assessment of Xanthines
  • References
  • Chapter 9 Mucus-Controlling Drug Therapy
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Drug Control of Mucus: A Perspective
  • Physiology of the Mucociliary System
  • Nature of Mucus Secretion
  • Physical Properties of Mucus
  • Mucoactive Agents
  • Mucolytics and Expectorants
  • Mucokinetic Agents
  • Mucoregulatory Medications
  • Other Mucoactive Agents
  • Gene Therapy
  • Using Mucoactive Therapy With Physiotherapy and Airway Clearance Devices
  • Future Mucus-Controlling Agents
  • Respiratory Care Assessment of Mucoactive Drug Therapy
  • References
  • Chapter 10 Surfactant Agents
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Physical Principles
  • Clinical Indications for Exogenous Surfactants
  • Identification of Surfactant Preparations
  • Specific Exogenous Surfactant Preparations
  • Hazards and Complications of Surfactant Therapy
  • Future Directions in Surfactant Therapy
  • Respiratory Care Assessment of Surfactant Therapy
  • References
  • Chapter 11 Corticosteroids in Respiratory Care
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Clinical Indications for Use of Inhaled Corticosteroids
  • Identification of Aerosolized Corticosteroids
  • Physiology of Corticosteroids
  • Nature of Inflammatory Response
  • Aerosolized Corticosteroids
  • Pharmacology of Corticosteroids
  • Hazards and Side Effects of Steroids
  • Clinical Application of Aerosol Steroids
  • Respiratory Care Assessment of Inhaled Corticosteroid Therapy
  • References
  • Chapter 12 Nonsteroidal Antiasthma Agents
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Clinical Indications for Nonsteroidal Antiasthma Agents
  • Identification of Nonsteroidal Antiasthma Agents
  • Mechanisms of Inflammation in Asthma
  • Cromolyn-Like (Mast Cell–Stabilizing) Agents
  • Antileukotriene Agents
  • Respiratory Care Assessment of Nonsteroidal Antiasthma Agents
  • References
  • Chapter 13 Aerosolized Antiinfective Agents
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Clinical Indications for Aerosolized Antiinfective Agents
  • Identification of Aerosolized Antiinfective Agents
  • Respiratory Care Assessment of Aerosolized Antiinfective Agents
  • References
  • Chapter 14 Antimicrobial Agents
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Principles of Antimicrobial Therapy
  • Identification of Pathogen
  • Susceptibility Testing and Resistance
  • Host Factors
  • Pharmacodynamics
  • Antimicrobial Combinations
  • Monitoring Response to Therapy
  • Antibiotics
  • Antimycobacterials
  • Antifungals
  • Antiviral Agents
  • Biologics
  • Respiratory Care Assessment of Antibiotic Therapy
  • References
  • Chapter 15 Cold and Cough Agents
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Sympathomimetic (Adrenergic) Decongestants
  • Antihistamine Agents
  • Expectorants
  • Cough Suppressants (Antitussives)
  • Cold Compounds
  • Respiratory Care Assessment of Cold and Cough Agents
  • References
  • Chapter 16 Selected Agents of Pulmonary Value
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • α1-Proteinase Inhibitor (Human)
  • Respiratory Care Assessment of Therapy of α1-Proteinase Inhibitor (Human)
  • Smoking Cessation Drug Therapy
  • E-Cigarettes
  • Respiratory Care Assessment of Smoking Cessation Drug Therapy
  • Nitric Oxide
  • Respiratory Care Assessment of Nitric Oxide
  • Synthetic Analogs of Prostacyclin
  • Respiratory Care Assessment of Synthetic Analogs of Prostacyclin
  • Phosphodiesterase 4 Inhibitor
  • Respiratory Care Assessment of Phosphodiesterase 4 Inhibitor
  • Cystic Fibrosis Transmembrane Conductance Regulators
  • Respiratory Care Assessment of CFTR Agents
  • Insulin Human (Recombinant DNA Origin)
  • Respiratory Care Assessment of Inhaled Insulin
  • References
  • Chapter 17 Neonatal and Pediatric Aerosolized Drug Therapy
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Off-Label Use of Drugs in Neonatal and Pediatric Patients
  • Factors Affecting Neonatal and Pediatric Aerosol Drug Delivery
  • Nebulized Drug Distribution
  • Clinical Response to Aerosolized Drugs in Neonatal and Pediatric Patients
  • Selection of Delivery Devices
  • Use of Selective Agents in Neonatal and Pediatric Patients
  • Adherence, Compliance, and Cooperation During Aerosol Therapy
  • Parent Education on Inhalation Therapy
  • Aerosol Administration in Intubated Neonatal and Pediatric Patients
  • Summary
  • References
  • Unit C Critical Care, Cardiovascular, and Polysomnography Agents
  • Chapter 18 Skeletal Muscle Relaxants (Neuromuscular Blocking Agents)
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Uses of Neuromuscular Blocking Agents
  • Physiology of the Neuromuscular Junction
  • Nondepolarizing Agents
  • Depolarizing Agents
  • Neuromuscular Blocking Agents and Mechanical Ventilation
  • Monitoring of Neuromuscular Blockade
  • References
  • Chapter 19 Diuretic Agents
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Renal Structure and Function
  • Diuretic Groups
  • Diuretic Combinations
  • Drug Interactions
  • Adverse Effects
  • Special Situations
  • References
  • Chapter 20 Drugs Affecting the Central Nervous System
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Neurotransmitters
  • Psychiatric Medications
  • Ethyl Alcohol
  • Pain Treatment
  • Chronic Pain Syndromes
  • Anesthesia
  • Central Nervous System and Respiratory Stimulants
  • References
  • Chapter 21 Vasopressors, Inotropes, and Antiarrhythmic Agents
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Overview of Cardiovascular System
  • Agents Used in the Management of Shock
  • Electrophysiology of Myocardium
  • Pharmacology of Antiarrhythmics
  • Management and Pharmacotherapy of Advanced Cardiac Life Support
  • Alternative Routes of Medication Administration
  • References
  • Chapter 22 Drugs Affecting Circulation: Antihypertensives, Antianginals, Antithrombotics
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • Hypertension
  • Hypertension Pharmacotherapy
  • Angina
  • Antithrombotic Agents
  • References
  • Chapter 23 Sleep and Sleep Pharmacology
  • Chapter Outline
  • Objectives
  • Key Terms and Definitions
  • History of Treatment of Sleep Disorders
  • Progession of Sleep
  • Neurophysiologic Mechanisms
  • Sleep Disorders: Causes and Treatments
  • References
  • Appendix A Answers to Self-Assessment Questions and Clinical Scenarios
  • Appendix B Units and Systems of Measurement
  • Appendix C Acceptable Mixtures of Most Commonly Prescribed Respiratory Care Drugs
  • Glossary
  • Index