List of Contributors, vii
Introduction, xiii
1 Central Nervous System Manifestations of Chromosomal Change, 1
Joseph R. Siebert
2 Neural Tube Defects, 13
Andrew J. Copp and Brian N. Harding
3 Midline Patterning Defects, 29
Edwin S. Monuki and Jeffrey A. Golden
4 Microcephaly, 41
Sandrine Passemard, Annie Laquerriere, ` Nathalie Journiac, and Pierre Gressens
5 Hemimegalencephaly and Dysplastic Megalencephaly, 55
Ghayda Mirzaa, Achira Roy, William B. Dobyns, Kathleen Millen, and Robert F. Hevner
6 Lissencephaly, Type I, 63
Jeffrey A. Golden
7 Lissencephaly, Type II (Cobblestone Lissencephaly), 75
Jeffrey A. Golden
8 Polymicrogyria, 85
Jeffrey A. Golden
9 Cerebral Heterotopia, 91
Edwin S. Monuki and Keith L. Ligon
10 Hippocampal Sclerosis, Granule Cell Dispersion, and Cortical Dysplasia, 101
Maria Thom
11 Tuberous Sclerosis Complex, 117
Shino D. Magaki and Harry V. Vinters
12 Chiari Malformations, 133
Homa Adle-Biassette and Jeffrey A. Golden
13 Dandy–Walker Malformation, Mega Cisterna Magna, and Blake’s Pouch Cyst, 141
Robert F. Hevner, Kathleen Millen, and William B. Dobyns
14 Joubert Syndrome, 151
Robert F. Hevner, William B. Dobyns, and Enza Maria Valente
15 Cerebellar Heterotopia and Dysplasia, 159
Marie Rivera-Zengotita and Anthony T. Yachnis
16 Brainstem Malformations, 167
Brian N. Harding
17 Spinal Cord Lesions, 179
Annie Laquerriere and Florent Marguet
18 Hydrocephalus, 187
Homa Adle-Biassette
19 Antenatal Disruptive Lesions, 199
Brian N. Harding
20 Hemorrhagic Lesions, 203
Marc R. Del Bigio
21 White Matter Lesions in the Perinatal Period, 213
Robin L. Haynes and Rebecca D. Folkerth
22 Gray Matter Lesions, 229
Marc R. Del Bigio
23 Pediatric Head Injury, 241
Colin Smith, Thomas S. Jacques, and R. Ross Reichard
24 Pediatric Vascular Malformations, 251
Shino D. Magaki, Randy Tashjian, and Harry V. Vinters
25 Sudden Infant Death Syndrome, 269
Hannah C. Kinney, Marco M. Hefti, Richard D. Goldstein, and Robin L. Haynes
26 Kernicterus, 281
Mariarita Santi and Lucy B. Rorke
27 Lesions Induced by Toxins, 285
Mariarita Santi, Lucy B. Rorke, and Catherine Keohane
28 Disorders of Carbohydrate Metabolism, 293
Josefine Radke, Carsten G. Bonnemann, ¨ Werner Stenzel, and Hans-H. Goebel
29 Sphingolipidoses and Related Disorders, 313
Annie Laquerriere, Soumeya Bekri, Kinoko Suzuki, and Brian N. Harding
30 The Neuronal Ceroid Lipofuscinoses, 369
Josefine Radke, Krystina E. Wisniewski, Werner Stenzel, and Hans-H. Goebel
31 Peroxisomal Disorders, 381
Phyllis L. Faust
32 Mitochondrial Disorders, 393
Anders Oldfors and Brian N. Harding
33 Disorders of Amino Acid Metabolism and Canavan Disease, 403
Dimitri P. Agamanolis
34 Pelizaeus–Merzbacher Disease, 417
Brian N. Harding
35 Cockayne Syndrome, 427
Karen M. Weidenheim and P. J. Brooks
36 Vanishing White Matter Disease, 437
Marianna Bugiani, James M. Powers, and Marjo S. van der Knaap
37 Alexander Disease, 447
James E. Goldman and Mel B. Feany
38 Neuroaxonal Dystrophy/Neurodegeneration with Brain Iron Accumulation, 455
Abi Li, Sarah Wiethoff, Charles Arber, Henry Houlden, Tamas Revesz, and Janice L. Holton
39 Spinal Muscular Atrophy, 469
Brian N. Harding
40 Autism Spectrum Disorders, 477
Matthew P. Anderson
41 Intrauterine Infections, 497
Catherine Keohane and Homa Adle-Biassette
42 Perinatal and Postnatal Infections, 511
Catherine Keohane
43 Rasmussen Encephalitis, 531
Harry V. Vinters, Shino D. Magaki, and Geoffrey C. Owens
Index, 537
