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Diagnostic Pathology: Molecular Oncology, 3rd Edition

Mohammad A Vasef, Aaron Auerbach
ISBN: 9780443112201
ISBN: 9780443112201
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Διαστάσεις 28 × 22 cm
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Περιγραφή

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Providing a clear understanding of molecular pathology as it relates to the transformation and pathogenesis of cancer in an era of personalized medicine, it incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Molecular Oncology is a visually stunning, one-stop resource for every practicing pathologist, hematopathologist, molecular pathologist, oncologist, or pathologist in training as an ideal day-to-day reference or as a reliable learning resource.
New to this edition
Molecular oncology is a rapidly evolving field with tremendous amounts of information that is new since the 2e published in March 2019. There is new molecular genetic data linked to either new targeted therapies or that serves as diagnostic or prognostic indicators. The 3e will include 8-10 new chapters and substantial updates and rewrites to existing contents to make sure ongoing edits and revisions to the upcoming WHO Classification of Hematopoietic Tumors are included in the 3e. The authors provide guidance on selecting the right test(s) at the right time for the right patient and comparisons of molecular testing methods (i.e., FSH testing vs. cytogenetics) are included. The market lacks a definitive source of all the recent changes, and DP3 Molecular Oncology will provide a comprehensive information source.
Key Features
  • Provides up-to-date, comprehensive coverage of relevant molecular tests and their clinical applications, along with organ-based chapters on the molecular genetic data relevant to individual disease entities
  • Contains new chapters and substantial revisions to existing content that include updates from the 2022 International Consensus Classification and the WHO Classification of Haematolymphoid Tumours, fifth edition
  • Provides expert guidance on selecting the right test(s) at the right time, as well as comparisons of molecular testing methods (e.g., FISH vs. cytogenetics)
  • Includes current information for new actionable mutations and targeted therapies
  • Covers ultrasensitive molecular techniques for minimal residual disease detection and disease monitoring
  • Discusses circulating cell-free DNA analysis for detection of resistance-associated mutations and disease monitoring, and provides usage details
  • Features an image-rich layout with more than 2,400 print and online-only images, including high-resolution H&E stains, immunostains, FISH images, gross pathology and clinical photographs, detailed full-color medical illustrations, and informative diagrams, charts, and schematics
  • Employs consistently templated chapters, bulleted content, key facts, a variety of tables, annotated images, pertinent references, and an extensive index for quick, expert reference at the point of care
  • Includes an eBook version that enables you to access all text, figures, and references with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date

Περιεχόμενα

Cover image
Title page
Table of Contents
Copyright
DEDICATIONS
CONTRIBUTING AUTHORS
PREFACE
ACKNOWLEDGMENTS
List of Tables
SECTIONS
SECTION 1: INTRODUCTION
Chapter 1: Structure of Chromosomes and Nucleic Acids
Main Text
Tables
Image Gallery
Chapter 2: DNA Replication, Transcription, and Translation
Main Text
Image Gallery
Chapter 3: Gene Mutations
Main Text
Image Gallery
SECTION 2: COMMON TECHNIQUES FOR ANALYSIS OF ALTERATIONS IN CHROMOSOMES AND DNA
Chapter 4: Cytogenetics and FISH
Main Text
Tables
Image Gallery
Chapter 5: Chromosomal Microarray
Main Text
Image Gallery
Chapter 6: Amplification Methods
Main Text
Image Gallery
Chapter 7: DNA High-Resolution Melting Curve Analysis
Main Text
Image Gallery
Chapter 8: Sequencing Technologies
Main Text
Tables
Image Gallery
Chapter 9: High-Throughput Methods in Molecular Pathology
Main Text
Chapter 10: DNA Methylation Analysis
Main Text
Image Gallery
SECTION 3: MOLECULAR GENETIC TESTS IN HEMATOPOIETIC TUMORS
Chapter 11: BCR::ABL1 Fusion
Main Text
Image Gallery
Chapter 12: PML::RARA Fusion
Main Text
Image Gallery
Chapter 13: Reverse Transcription PCR for Myeloid Leukemia Transcripts
Main Text
Image Gallery
Chapter 14: FLT3, NPM1, and CEBPA Mutations
Main Text
Image Gallery
Chapter 15: JAK2 Mutations and Rearrangements
Main Text
Image Gallery
Chapter 16: MPL Mutations
Main Text
Image Gallery
Chapter 17: Calreticulin (CALR) Mutations
Main Text
Image Gallery
Chapter 18: CSF3R Mutations
Main Text
Image Gallery
Chapter 19: SETBP1 Mutations
Main Text
Image Gallery
Chapter 20: KIT Mutations
Main Text
Tables
Image Gallery
Chapter 21: IDH1 and IDH2 Mutations
Main Text
Image Gallery
Chapter 22: Other Mutations and Gene Panel Testing in Myeloid Neoplasms
Main Text
Tables
Image Gallery
Chapter 23: Immunoglobulin Heavy (IGH) Chain Gene Rearrangements
Main Text
Image Gallery
Chapter 24: T-Cell Receptor Gamma (TRG) and Delta (TRD) Chain Rearrangements
Main Text
Image Gallery
Chapter 25: T-Cell Receptor Beta (TRB) Chain Gene Rearrangements
Main Text
Image Gallery
Chapter 26: Southern Blot Analysis of Antigen Receptor Genes
Main Text
Image Gallery
Chapter 27: EBV-Associated Human Neoplasms
Main Text
Image Gallery
Chapter 28: MYD88 Mutation
Main Text
Image Gallery
Chapter 29: NOTCH1 Mutation
Main Text
Image Gallery
Chapter 30: EZH2 Mutation
Main Text
Image Gallery
SECTION 4: MOLECULAR GENETIC TESTS IN SOLID TUMORS, BONE AND SOFT TISSUE TUMORS, AND CNS TUMORS
Chapter 31: ALK Rearrangements and Mutations
Main Text
Image Gallery
Chapter 32: ROS1 Rearrangements
Main Text
Image Gallery
Chapter 33: RET Rearrangements
Main Text
Tables
Image Gallery
Chapter 34: FISH for MET Amplifications
Main Text
Image Gallery
Chapter 35: FISH for ERBB2 (HER2) Amplifications
Main Text
Image Gallery
Chapter 36: KRAS Mutations
Main Text
Image Gallery
Chapter 37: BRAF Mutations
Main Text
Image Gallery
Chapter 38: EGFR Mutations
Main Text
Image Gallery
Chapter 39: Targeted Hotspot Gene Panel Using Massively Parallel Sequencing (Next-Generation Sequencing)
Main Text
Image Gallery
Chapter 40: Targeted Hotspot Gene Panel Table
Main Text
Chapter 41: MGMT Promoter Gene Methylation Assay
Main Text
Image Gallery
SECTION 5: MOLECULAR PATHOLOGY OF MYELOID NEOPLASMS
Chapter 42: Molecular Work-Up of Myeloid Neoplasms
Main Text
Tables
Image Gallery
MYELOPROLIFERATIVE NEOPLASMS
Chapter 43: Chronic Myeloid Leukemia, BCR::ABL1-Positive
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 44: Chronic Neutrophilic Leukemia
Key Facts
Key Images
Main Text
Image Gallery
Chapter 45: Polycythemia Vera
Key Facts
Key Images
Main Text
Image Gallery
Chapter 46: Primary Myelofibrosis
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 47: Essential Thrombocythemia
Key Facts
Key Images
Main Text
Image Gallery
Chapter 48: Chronic Eosinophilic Leukemia, NOS
Key Facts
Key Images
Main Text
Chapter 49: Myeloproliferative Neoplasm, Unclassifiable
Key Facts
Key Images
Main Text
Image Gallery
MASTOCYTOSIS
Chapter 50: Mastocytosis
Key Facts
Key Images
Main Text
Image Gallery
MYELOID/LYMPHOID NEOPLASMS WITH EOSINOPHILIA AND GENE REARRANGEMENT
Chapter 51: Myeloid/Lymphoid Neoplasms With Eosinophilia and Tyrosine Kinase Gene Fusions
Main Text
Image Gallery
PREMALIGNANT CLONAL HEMATOPOIESIS AND CYTOPENIAS
Chapter 52: VEXAS Syndrome
Key Facts
Key Images
Main Text
Image Gallery
Chapter 53: Clonal Hematopoiesis and Premalignant Clonal Cytopenia
Key Facts
Key Images
Main Text
MYELODYSPLASTIC SYNDROME (MDS)
Chapter 54: Overview and Classification of Myelodysplastic Syndrome
Main Text
Tables
Image Gallery
Chapter 55: Myelodysplastic Syndrome With Mutated SF3B1
Key Facts
Key Images
Main Text
Image Gallery
Chapter 56: Myelodysplastic Syndrome, NOS
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 57: Myelodysplastic Syndrome With del(5q)
Key Facts
Key Images
Main Text
Image Gallery
Chapter 58: Myelodysplastic Syndrome With TP53 Multihit Mutations
Key Facts
Key Images
Main Text
Tables
Chapter 59: Myelodysplastic Syndrome/Acute Myeloid Leukemia
Key Facts
Key Images
Main Text
Chapter 60: Pediatric Myelodysplastic Syndrome and Refractory Cytopenia of Childhood
Key Facts
Key Images
Main Text
Image Gallery
MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASMS
Chapter 61: Overview of Myelodysplastic/Myeloproliferative Neoplasms
Main Text
Image Gallery
Chapter 62: Chronic Myelomonocytic Leukemia
Key Facts
Key Images
Main Text
Image Gallery
Chapter 63: Atypical Chronic Myeloid Leukemia
Key Facts
Key Images
Main Text
Image Gallery
Chapter 64: Juvenile Myelomonocytic Leukemia
Key Facts
Key Images
Main Text
Chapter 65: Myelodysplastic/Myeloproliferative Neoplasm, NOS
Key Facts
Key Images
Main Text
Image Gallery
ACUTE MYELOID LEUKEMIA
Chapter 66: Overview of Acute Myeloid Leukemia
Main Text
Tables
Image Gallery
Chapter 67: Acute Myeloid Leukemia With t(8;21)/RUNX1::RUNX1T1
Key Facts
Key Images
Main Text
Image Gallery
Chapter 68: Acute Myeloid Leukemia With inv(16) or t(16;16)/CBFB::MYH11
Key Facts
Key Images
Main Text
Image Gallery
Chapter 69: Acute Promyelocytic Leukemia With t(15;17)/PML::RARA
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 70: Acute Myeloid Leukemia With t(9;11)/MLLT3::KMT2A
Key Facts
Key Images
Main Text
Image Gallery
Chapter 71: Acute Myeloid Leukemia With t(6:9)/DEK::NUP214
Key Facts
Key Images
Main Text
Chapter 72: Acute Myeloid Leukemia With inv(3) or t(3;3)/GATA2; MECOM
Key Facts
Key Images
Main Text
Chapter 73: Acute Myeloid Leukemia (Megakaryoblastic) With t(1;22)/RBM15::MRTFA
Key Facts
Key Images
Main Text
Chapter 74: Acute Myeloid Leukemia With Myelodysplasia-Related Gene Mutations or Cytogenetic Abnormalities
Key Facts
Key Images
Main Text
Image Gallery
Chapter 75: Acute Myeloid Leukemia, NOS
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 76: Myeloid Sarcoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 77: Myeloid Proliferations Associated With Down Syndrome
Key Facts
Key Images
Main Text
Image Gallery
BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM
Chapter 78: Blastic Plasmacytoid Dendritic Cell Neoplasm
Key Facts
Key Images
Main Text
Image Gallery
SECTION 6: MOLECULAR PATHOLOGY OF LYMPHOID NEOPLASMS
Chapter 79: Overview of Lymphoid Neoplasms
Main Text
Tables
Image Gallery
Chapter 80: Molecular Work-Up of Lymphoid Neoplasms
Main Text
Image Gallery
DETERMINATION OF CLONALITY IN B-, T-, AND NK-CELL NEOPLASMS
Chapter 81: Lymphoma-Associated Chromosomal Translocations
Main Text
Image Gallery
PRECURSOR LYMPHOID NEOPLASMS
Chapter 82: B-Lymphoblastic Leukemia/Lymphoma With Recurrent Genetic Abnormalities
Key Facts
Key Images
Main Text
Image Gallery
Chapter 83: B-Lymphoblastic Leukemia/Lymphoma, BCR::ABL1-Like (Ph-Like ALL)
Main Text
Image Gallery
Chapter 84: T-Lymphoblastic Leukemia/Lymphoma
Key Facts
Key Images
Main Text
Image Gallery
MATURE B-CELL NEOPLASMS
Chapter 85: Small Lymphocytic Lymphoma/Chronic Lymphocytic Leukemia
Key Facts
Key Images
Main Text
Image Gallery
Chapter 86: B-Cell Prolymphocytic Leukemia
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 87: Splenic Marginal Zone Lymphoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 88: Hairy Cell Leukemia
Key Facts
Key Images
Main Text
Image Gallery
Chapter 89: Splenic B-Cell Lymphoma/Leukemia, Unclassifiable
Key Facts
Key Images
Main Text
Image Gallery
Chapter 90: Lymphoplasmacytic Lymphoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 91: Monoclonal Gammopathy of Undetermined Significance
Key Facts
Key Images
Main Text
Image Gallery
Chapter 92: Multiple Myeloma (Plasma Cell Myeloma)
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 93: Follicular Lymphoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 94: Mantle Cell Lymphoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 95: Diffuse Large B-Cell Lymphoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 96: Burkitt Lymphoma
Key Facts
Key Images
Main Text
Image Gallery
MATURE T- AND NK-CELL NEOPLASMS
Chapter 97: T-Cell Prolymphocytic Leukemia
Key Facts
Key Images
Main Text
Image Gallery
Chapter 98: Chronic Lymphoproliferative Disorder of NK Cells
Key Facts
Key Images
Main Text
Image Gallery
Chapter 99: Aggressive NK-Cell Leukemia
Key Facts
Key Images
Main Text
Image Gallery
Chapter 100: Extranodal NK-/T-Cell Lymphoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 101: Adult T-Cell Leukemia/Lymphoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 102: Intestinal T-Cell Lymphoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 103: Hepatosplenic T-Cell Lymphoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 104: Subcutaneous Panniculitis-Like T-Cell Lymphoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 105: Mycosis Fungoides/Sézary Syndrome
Key Facts
Key Images
Main Text
Image Gallery
Chapter 106: Primary Cutaneous CD30-Positive T-Cell Lymphoproliferative Disorders
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 107: Peripheral T-Cell Lymphoma, NOS
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 108: Nodal Follicular Helper T-Cell Lymphoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 109: Anaplastic Large Cell Lymphoma, ALK-Negative
Key Facts
Key Images
Main Text
Image Gallery
Chapter 110: Anaplastic Large Cell Lymphoma, ALK-Positive
Key Facts
Key Images
Main Text
Image Gallery
SECTION 7: MOLECULAR PATHOLOGY OF DENDRITIC CELL AND HISTIOCYTIC NEOPLASMS
Chapter 111: Histiocytic Sarcoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 112: Langerhans Cell Histiocytosis
Key Facts
Key Images
Main Text
Image Gallery
Chapter 113: Interdigitating Dendritic Cell Sarcoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 114: Follicular Dendritic Cell Sarcoma
Key Facts
Key Images
Main Text
Image Gallery
SECTION 8: MOLECULAR PATHOLOGY OF SOLID TUMORS
HEAD AND NECK, INCLUDING SINONASAL TUMORS AND SALIVARY GLANDS
Chapter 115: HPV-Associated Head and Neck Carcinomas
Key Facts
Key Images
Main Text
Image Gallery
Chapter 116: Head and Neck Mucosal Squamous Cell Carcinoma, Non-HPV Related
Key Facts
Key Images
Main Text
Image Gallery
Chapter 117: Important Alterations in Non-HPV-Related Head and Neck Squamous Cell Carcinoma
Main Text
Chapter 118: Translocation-Specific Salivary Gland Tumors
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 119: Translocation-Specific Salivary Gland Tumors (Continued)
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 120: Nasopharyngeal EBV-Related Squamous Cell Carcinoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 121: Other Head and Neck Tumors
Key Facts
Key Images
Main Text
Image Gallery
THYROID
Chapter 122: Papillary Thyroid Carcinoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 123: Follicular Thyroid Carcinoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 124: Poorly Differentiated Thyroid Carcinoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 125: Anaplastic Thyroid Carcinoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 126: Medullary Thyroid Carcinoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
LUNG
Chapter 127: Adenocarcinoma, Lung
Key Facts
Key Images
Main Text
Image Gallery
Chapter 128: Squamous Cell Carcinoma, Lung
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 129: Small Cell Neuroendocrine Carcinoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 130: Mesothelioma
Key Facts
Key Images
Main Text
Image Gallery
LUMINAL GASTROINTESTINAL TRACT
Chapter 131: Gastric Adenocarcinoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 132: Colorectal Adenocarcinoma and Precancerous Lesions
Key Facts
Key Images
Main Text
Image Gallery
Chapter 133: Gastrointestinal Stromal Tumor
Key Facts
Key Images
Main Text
Tables
Image Gallery
LIVER
Chapter 134: HNF1A-Inactivated Hepatocellular Adenoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 135: β-Catenin-Activated Hepatocellular Adenoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 136: Inflammatory Hepatocellular Adenoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 137: Hepatocellular Carcinoma
Key Facts
Key Images
Main Text
Image Gallery
PANCREATICOBILIARY
Chapter 138: Pancreatic Ductal Adenocarcinoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 139: Pancreatic Mucinous Cystic Neoplasm
Key Facts
Key Images
Main Text
Chapter 140: Pancreatic Intraductal Papillary Mucinous Neoplasm
Key Facts
Key Images
Main Text
Chapter 141: Cholangiocarcinoma
Key Facts
Key Images
Main Text
TESTIS
Chapter 142: Testicular Germ Cell Tumors
Main Text
Image Gallery
KIDNEY
Chapter 143: Clear Cell Renal Cell Carcinoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 144: Chromophobe Renal Cell Carcinoma
Key Facts
Key Images
Main Text
Chapter 145: Papillary Renal Cell Carcinoma
Key Facts
Key Images
Main Text
Chapter 146: TFE3-Rearranged and TFEB-Altered Renal Cell Carcinomas
Main Text
Image Gallery
Chapter 147: Wilms Tumor
Key Facts
Key Images
Main Text
Image Gallery
Chapter 148: Clear Cell Sarcoma of Kidney
Key Facts
Key Images
Main Text
Chapter 149: Oncocytoma
Key Facts
Key Images
Main Text
Chapter 150: Rhabdoid Tumor of Kidney
Key Facts
Key Images
Main Text
BLADDER
Chapter 151: Urothelial Carcinoma
Key Facts
Key Images
Main Text
Image Gallery
ADRENAL
Chapter 152: Pheochromocytoma/Paraganglioma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 153: Adrenal Cortical Carcinoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 154: Neuroblastoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 155: Adrenal Cortical Adenoma
Key Facts
Key Images
Main Text
Image Gallery
PROSTATE
Chapter 156: Prostatic Adenocarcinoma, Acinar Type and High-Grade Prostatic Intraepithelial Neoplasia
Key Facts
Key Images
Main Text
Image Gallery
BREAST
Chapter 157: ADH and DCIS (Dysplastic, Premalignant)
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 158: Ductal Carcinomas
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 159: Lobular Carcinoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 160: Invasive Ductal Carcinoma of No Special Type With Medullary Features
Key Facts
Key Images
Main Text
Image Gallery
Chapter 161: Metaplastic Breast Carcinoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 162: Phyllodes Tumors
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 163: Basal-Like and Triple-Negative Breast Carcinomas
Key Facts
Key Images
Main Text
Tables
Image Gallery
CERVIX/VULVA/VAGINA
Chapter 164: Preneoplastic Conditions, Cervix/Vulva/Vagina
Key Facts
Key Images
Main Text
Image Gallery
Chapter 165: Squamous Cell Carcinoma, Cervix/Vulva/Vagina
Key Facts
Key Images
Main Text
Image Gallery
Chapter 166: Adenocarcinoma, Cervix/Vulva/Vagina
Key Facts
Key Images
Main Text
Image Gallery
UTERUS
Chapter 167: Endometrial Intraepithelial Neoplasia
Key Facts
Key Images
Main Text
Chapter 168: Uterine Endometrioid Carcinoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 169: Uterine Serous Carcinoma
Key Facts
Key Images
Main Text
Chapter 170: Clear Cell Carcinoma, Uterus
Key Facts
Key Images
Main Text
Image Gallery
Chapter 171: Uterine Sarcomas
Main Text
Tables
Image Gallery
OVARIES/FALLOPIAN TUBE
Chapter 172: Serous Tumors of Ovary and Fallopian Tube
Key Facts
Key Images
Main Text
Image Gallery
Chapter 173: Other Surface Epithelial Tumors of Ovary
Key Facts
Key Images
Main Text
Image Gallery
Chapter 174: Sex Cord-Stromal Tumors of Ovary
Key Facts
Key Images
Main Text
Image Gallery
Chapter 175: Germ Cell Tumor, Ovary
Key Facts
Key Images
Main Text
Image Gallery
SKIN
Chapter 176: Premalignant Conditions, Skin
Key Facts
Key Images
Main Text
Image Gallery
Chapter 177: Melanoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 178: Squamous Cell Carcinoma, Skin
Key Facts
Key Images
Main Text
Image Gallery
Chapter 179: Basal Cell Carcinoma, Skin
Key Facts
Key Images
Main Text
Image Gallery
Chapter 180: Sebaceous Tumors
Key Facts
Key Images
Main Text
Image Gallery
Chapter 181: Dermatofibroma and Dermatofibrosarcoma Protuberans
Key Facts
Key Images
Main Text
Image Gallery
BONE
Chapter 182: Overview of Molecular Pathology of Bone and Soft Tissue Tumors
Main Text
Tables
Image Gallery
Chapter 183: Osteosarcomas
Main Text
Image Gallery
Chapter 184: Ewing Sarcoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 185: Other Small Round Blue Cell Sarcomas
Main Text
Image Gallery
Chapter 186: Giant Cell Tumor of Bone
Key Facts
Key Images
Main Text
Image Gallery
Chapter 187: Intermediate and Malignant Cartilaginous Tumors of Bone
Main Text
Image Gallery
SOFT TISSUE
Chapter 188: Intermediate and Malignant Myofibroblastic/Fibroblastic Tumors
Main Text
Tables
Image Gallery
Chapter 189: Liposarcomas
Main Text
Image Gallery
Chapter 190: Muscle Sarcomas
Main Text
Image Gallery
Chapter 191: Intermediate and Malignant Vascular Tumors
Main Text
Image Gallery
Chapter 192: Malignant Peripheral Nerve Sheath Tumor
Key Facts
Key Images
Main Text
Image Gallery
Chapter 193: Representative Genetic Findings in Bone and Soft Tissue Tumors
Main Text
SARCOMAS OF UNCERTAIN DIFFERENTIATION
Chapter 194: Rare Sarcomas of Uncertain Differentiation With Specific Molecular Alterations
Main Text
Tables
Image Gallery
Chapter 195: Rare Sarcomas of Uncertain Differentiation With Specific Molecular Alterations (Continued)
Main Text
Tables
Image Gallery
CNS
Chapter 196: Glioblastoma, IDH Wildtype
Key Facts
Key Images
Main Text
Image Gallery
Chapter 197: Astrocytoma, IDH-Mutant
Key Facts
Key Images
Main Text
Image Gallery
Chapter 198: Pilocytic Astrocytoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 199: Oligodendroglioma, IDH Mutant, and 1p/19q Codeleted
Key Facts
Key Images
Main Text
Image Gallery
Chapter 200: Ependymal Tumors
Key Facts
Key Images
Main Text
Image Gallery
Chapter 201: Medulloblastoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 202: Choroid Plexus Tumors
Key Facts
Key Images
Main Text
Image Gallery
Chapter 203: Meningioma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 204: Retinoblastoma
Key Facts
Key Images
Main Text
Image Gallery
SECTION 9: QUALITY ASSURANCE AND REGULATORY ISSUES
Chapter 205: Federal Agencies and Regulation of Laboratories
Main Text
Chapter 206: FDA Regulations
Main Text
Chapter 207: Proficiency Testing and Accreditation
Main Text
INDEX

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