Availability: Άμεσα Διαθέσιμο

Berne & Levy Physiology, 8th Edition

ISBN: 9780323847902
Εκδόσεις:
Διαστάσεις 28 × 22 cm
Μορφή

Εκδόσεις

Ημ. Έκδοσης

Σελίδες

Έκδοση

Συγγραφείς

, ,

Κύριος Συγγραφέας

Original price was: 105,00€.Η τρέχουσα τιμή είναι: 93,00€.(Περιλαμβάνεται ΦΠΑ 6%)

Άμεσα Διαθέσιμο

Περιγραφή

Pairing necessary detail with concise readability, Berne & Levy Physiology, 8th Edition, provides a perfect balance of content to deliver an in-depth understanding of the body’s dynamic processes. Long respected for its scientifically rigorous approach, this highly regarded, mid-size text offers essential physiology with integrated coverage of biophysics and key experimental observations and examples—all designed to provide a solid scientific foundation in physiology for future scientists and clinicians.

 

Key Features
  • Uses a logical, organ system-based approach that clearly describes all of the mechanisms that control and regulate bodily function.
  • Includes new clinical case examples, as well as In the Clinic and At the Molecular Level boxes that highlight practical aspects of this fundamental science.
  • Provides key experimental observations and examples that offer a rich understanding of the body’s dynamic processes.
  • Discusses recent discoveries such as the role of lymphatics in the nervous system.
  • Begins each chapter with a bulleted list of questions and ends with key concepts covered in that chapter.
  • Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Περιεχόμενα

  • Cover Image
  • Title Page
  • Copyright
  • Dedication
  • Section Authors
  • Preface
  • Note to Instructors
  • Table of Contents
  • Section 1 Cellular Physiology
  • Chapter 1 Principles of Cell and Membrane Function
  • Learning Objectives
  • Overview of Eukaryotic Cells
  • Vesicular Transport
  • Electrochemical Gradient
  • Osmosis and Osmotic Pressure
  • Key Points
  • Chapter 2 Homeostasis: Volume and Composition of Body Fluid Compartments
  • Learning Objectives
  • Concept of Steady-State Balance
  • Volumes and Composition of Body Fluid Compartments
  • Maintenance of Cellular Homeostasis
  • Principles of Epithelial Transport
  • Key Concepts
  • Chapter 3 Signal Transduction, Membrane Receptors, Second Messengers, and Regulation of Gene Expression
  • Learning Objectives
  • Cell-to-Cell Communication
  • Receptors
  • Receptors and Signal Transduction Pathways
  • Regulation of Gene Expression by Signal Transduction Pathways
  • Key Points
  • Section 2 Neurophysiology
  • Chapter 4 The Nervous System: Introduction to Cells and Systems
  • Learning Objectives
  • Cellular Components of the Nervous System
  • The Peripheral Nervous System
  • The Central Nervous System
  • Nervous Tissue Reactions to Injury
  • Key Points
  • Chapter 5 Generation and Conduction of Action Potentials
  • Learning Objectives
  • Membrane Potentials
  • Suprathreshold Response: The Action Potential
  • Conduction of Action Potentials
  • Key Points
  • Chapter 6 Synaptic Transmission
  • Learning Objectives
  • Electrical Synapses
  • Chemical Synapses
  • Synaptic Integration
  • Modulation of Synaptic Activity
  • Neurotransmitters
  • Neurotransmitter Receptors
  • Key Points
  • Chapter 7 The Somatosensory System
  • Learning Objectives
  • Subdivisions of the Somatosensory System
  • Discriminatory Touch and Proprioception
  • Thalamic and Cortical Somatosensory Areas
  • Pain and Temperature Sensation
  • Transduction in the Somatosensory System
  • Centrifugal Control of Somatosensation
  • Key Points
  • Chapter 8 The Special Senses
  • Learning Objectives
  • The Visual System
  • The Auditory and Vestibular Systems
  • The Chemical Senses
  • Key Points
  • Chapter 9 Organization of Motor Function
  • Learning Objectives
  • Principles of Spinal Cord Organization
  • Descending Motor Pathways
  • Brainstem Control of Posture and Movement
  • Motor Control by the Cerebral Cortex
  • Motor Control by the Cerebellum
  • Motor Control by the Basal Ganglia
  • Eye Movement
  • Key Points
  • Chapter 10 Integrative Functions of the Nervous System
  • Learning Objectives
  • The Cerebral Cortex
  • Key Points
  • Chapter 11 The Autonomic Nervous System and Its Central Control
  • Learning Objectives
  • Organization of the Autonomic Nervous System
  • Autonomic Ganglia
  • Neurotransmitters
  • Central Control of Autonomic Function
  • Key Points
  • Section 3 Muscle Physiology
  • Chapter 12 Skeletal Muscle Physiology
  • Learning Objectives
  • Skeletal Muscle Physiology
  • Organization of Skeletal Muscle
  • Control of Skeletal Muscle Activity
  • Skeletal Muscle Types
  • Modulation of the Force of Contraction
  • Modulation of Force by Reflex Arcs
  • Skeletal Muscle Tone
  • Energy Sources During Contraction
  • Oxygen Debt
  • Fatigue
  • Growth and Development
  • Denervation, Reinnervation, and Cross-Innervation
  • Response to Exercise
  • Delayed-Onset Muscle Soreness
  • Biophysical Properties of Skeletal Muscle
  • Key Points
  • Chapter 13 Cardiac Muscle
  • Learning Objectives
  • Basic Organization of Cardiac Muscle Cells
  • Control of Cardiac Muscle Activity
  • Regulation of the Force of Contraction
  • Cardiac Muscle Metabolism
  • Cardiac Muscle Hypertrophy
  • Key Concepts
  • Chapter 14 Smooth Muscle
  • Learning Objectives
  • Overview of Smooth Muscle
  • Structure of Smooth Muscle Cells
  • Control of Smooth Muscle Activity
  • Innervation of Smooth Muscle
  • Regulation of Contraction
  • Regulation of Myoplasmic Calcium Concentration
  • Development and Hypertrophy
  • Synthetic and Secretory Functions
  • Biophysical Properties of Smooth Muscle
  • Key Points
  • Section 4 Cardiovascular Physiology
  • Chapter 15 Overview of Circulation
  • Learning Objectives
  • The Heart
  • The Cardiovascular Circuit
  • Blood Vessels
  • Key Points
  • Chapter 16 Elements of Cardiac Function
  • Learning Objectives
  • Overview of Cardiac Function
  • Electrical Properties of the Heart
  • Normal Sinus Rhythm
  • Arrhythmogenic Mechanisms
  • Electrocardiography
  • Arrhythmias
  • The Cardiac Pump
  • Key Points
  • Chapter 17 Properties of the Vasculature
  • Learning Objectives
  • Hemodynamics
  • The Arterial System
  • The Venous System
  • Microcirculation and Lymphatic System
  • Coronary Circulation
  • Cutaneous Circulation
  • Skeletal Muscle Circulation
  • Cerebral Circulation
  • Intestinal Circulation
  • Hepatic Circulation
  • Fetal Circulation
  • Key Points
  • Chapter 18 Regulation of the Heart and Vasculature
  • Learning Objectives
  • Regulation of Heart Rate and Myocardial Performance
  • Nervous Control of the Heart Rate
  • Regulation of Myocardial Performance
  • Regulation of the Peripheral Circulation
  • Key Points
  • Chapter 19 Integrated Control of the Cardiovascular System
  • Learning Objectives
  • Regulation of Cardiac Output and Blood Pressure
  • Vascular Function Curve
  • Relating the Cardiac Function Curve to the Vascular Function Curve
  • A More Complete Theoretical Model: The Two-Pump System
  • Role of the Heart Rate in Control of Cardiac Output
  • Ancillary Factors That Affect the Venous System and Cardiac Output
  • Interplay of Central and Peripheral Factors in Control of the Circulation
  • Key Points
  • Section 5 Respiratory Physiology
  • Chapter 20 Introduction to the Respiratory System
  • Learning Objectives
  • Lung Anatomical Structure/Function Relationships
  • Circulatory Systems in the Lung
  • Innervation
  • Lung Embryology, Development, Aging, and Repair
  • Key Points
  • Chapter 21 Static Lung and Chest Wall Mechanics
  • Learning Objectives
  • Pressures in the Respiratory System
  • How a Pressure Gradient Is Created
  • Lung Volumes and Their Measurement
  • Lung Volumes and Capacities
  • Determinants of Lung Volume
  • Pressure-Volume Relationships
  • Lung Compliance
  • Surface Tension and Surfactant
  • Key Points
  • Chapter 22 Dynamic Lung and Chest Wall Mechanics
  • Learning Objectives
  • Dynamic Lung Mechanics
  • Work of Breathing
  • Key Concepts
  • Chapter 23 Ventilation, Perfusion, and Ventilation/Perfusion Relationships
  • Learning Objectives
  • Ventilation
  • Dead Space Ventilation: Anatomical and Physiological
  • Alveolar Ventilation
  • Pulmonary Vascular Resistance
  • Distribution of Pulmonary Blood Flow
  • Active Regulation of Blood Flow
  • Ventilation/Perfusion Relationships
  • Arterial Blood Hypoxemia, Hypoxia, and Hypercarbia
  • Low Ventilation/Perfusion
  • Alveolar Hypoventilation
  • Diffusion Abnormalities
  • Mechanisms of Hypercapnia
  • Effect of 100% Oxygen on Arterial Blood Gas Abnormalities
  • Regional Differences
  • Key Points
  • Chapter 24 Oxygen and Carbon Dioxide Transport
  • Learning Objectives
  • Gas Diffusion
  • Oxygen Transport
  • Carbon Dioxide Transport
  • Regulation of Hydrogen Ion Concentration and Acid-Base Balance
  • Carbon Dioxide Dissociation Curve
  • Key Points
  • Chapter 25 Control of Respiration
  • Learning Objectives
  • Ventilatory Control: An Overview
  • Response to Carbon Dioxide
  • Control of Ventilation: The Details
  • Exercise
  • Abnormalities in the Control of Breathing
  • Key Points
  • Chapter 26 Host Defense and Metabolism in the Lung
  • Learning Objectives
  • Host Defense
  • Epithelial Cells and Commensal Microbiota Protect the Lumen of the Airways
  • Clinical Manifestations Associated With Abnormalities in Mucosal Innate and Adaptive Immunity
  • Metabolic Functions of the Lung
  • Key Points
  • Section 6 Gastrointestinal Physiology
  • Chapter 27 Functional Anatomy and General Principles of Regulation in the Gastrointestinal Tract
  • Learning Objectives
  • Functional Anatomy
  • Regulatory Mechanisms in the Gastrointestinal Tract
  • Response of the GI Tract to a Meal
  • Key Concepts
  • Chapter 28 The Cephalic, Oral, and Esophageal Phases of the Integrated Response to a Meal
  • Learning Objectives
  • Cephalic and Oral Phases
  • Esophageal Phase
  • Key Concepts
  • Chapter 29 The Gastric Phase of the Integrated Response to a Meal
  • Learning Objectives
  • Functional Anatomy of the Stomach
  • Gastric Secretion
  • Digestion in the Stomach
  • Gastrointestinal Motility
  • Gastric Motility
  • Key Concepts
  • Chapter 30 The Small Intestinal Phase of the Integrated Response to a Meal
  • Learning Objectives
  • Gastric Emptying in the Small Intestinal Phase
  • Carbohydrate Assimilation
  • Protein Assimilation
  • Uptake of Peptides and Amino Acids
  • Lipid Assimilation
  • Water and Electrolyte Secretion and Absorption
  • Absorption of Minerals and Water-Soluble Vitamins
  • Motor Patterns of the Small Intestine
  • Key Concepts
  • Chapter 31 The Colonic Phase of the Integrated Response to a Meal
  • Learning Objectives
  • Overview of the Large Intestine
  • Key Concepts
  • Chapter 32 Transport and Metabolic Functions of the Liver
  • Learning Objectives
  • Overview of the Liver and its Functions
  • Structural Features of the Liver and Biliary System
  • Bile Formation and Secretion
  • Ammonia Handling by the Liver
  • Clinical Assessment of Liver Function
  • Key Concepts
  • Section 7 Renal Physiology
  • Chapter 33 Elements of Renal Function
  • Learning Objectives
  • Overview of Renal Function
  • Functional Anatomy of the Kidneys
  • Assessment of Renal Function
  • Glomerular Filtration
  • Renal Blood Flow
  • Regulation of Renal Blood Flow and Glomerular Filtration Rate
  • Key Points
  • Chapter 34 Solute and Water Transport Along the Nephron: Tubular Function
  • Learning Objectives
  • Solute and Water Reabsorption Along the Nephron
  • Regulation of NaCl and Water Reabsorption
  • Key Points
  • Chapter 35 Control of Body Fluid Osmolality and Volume
  • Learning Objectives
  • Control of Body Fluid Osmolality: Urine Concentration and Dilution
  • Control of Extracellular Fluid Volume and Regulation of Renal NaCl Excretion
  • Key Concepts
  • Chapter 36 Potassium, Calcium, and Phosphate Homeostasis
  • Learning Objectives
  • K+ Homeostasis
  • Regulation of Plasma [K+]
  • Alterations in Plasma [K+]
  • K+ Excretion by the Kidneys
  • Cellular Mechanism of K+ Transport by Principal and Intercalated Cells in the DT and CCD
  • K+ Excretion by the DT and CCD
  • Overview of Calcium and Inorganic Phosphate Homeostasis
  • Integrative Review of Parathyroid Hormone and Calcitriol on Ca++ and Pi Homeostasis
  • Key Concepts
  • Chapter 37 Role of the Kidneys in the Regulation of Acid-Base Balance
  • Learning Objectives
  • The HCO3− Buffer System
  • Overview of Acid-Base Balance
  • Net Acid Excretion by the Kidneys
  • Response to Acid-Base Disorders
  • Simple Acid-Base Disorders
  • Key Concepts
  • Section 8 Endocrine Physiology
  • Chapter 38 Introduction to the Endocrine System
  • Learning Objectives
  • Configuration of Feedback Loops Within the Endocrine System
  • Chemical Nature of Hormones
  • Transport of Hormones in the Circulation
  • Cellular Responses to Hormones
  • Key Concepts
  • Chapter 39 Hormonal Regulation of Energy Metabolism
  • Learning Objectives
  • Continual Energy Supply and Demand: The Challenge
  • Integrated Overview of Energy Metabolism
  • Pancreatic Hormones Involved in Metabolic Homeostasis During Different Metabolic Phases
  • Hormonal Regulation of Specific Metabolic Reactions and Pathways
  • Leptin and Energy Balance
  • Key Concepts
  • Chapter 40 Hormonal Regulation of Calcium and Phosphate Metabolism
  • Learning Objectives
  • Crucial Roles of Calcium and Phosphate in Cellular Physiology
  • Hormonal Regulation of Calcium and Phosphate: PTH, Vitamin D, and FGF23
  • Hormonal Effects on Target Organs
  • Regulation of Bone Formation
  • Integrated Physiological Regulation of Ca++/Pi Metabolism
  • Key Concepts
  • Chapter 41 The Hypothalamus and Pituitary Gland
  • Learning Objectives
  • Anatomy
  • The Neurohypophysis
  • The Adenohypophysis
  • Key Concepts
  • Chapter 42 The Thyroid Gland
  • Learning Objectives
  • Anatomy and Histology of the Thyroid Gland
  • Thyroid Hormones
  • Transport of Thyroid Hormones
  • Cellular Entry and Peripheral Conversion of Thyroid Hormones
  • Regulation of Thyroid Function
  • Physiological Effects of Thyroid Hormone
  • Key Concepts
  • Chapter 43 The Adrenal Gland
  • Learning Objectives
  • Anatomy
  • Adrenal Medulla
  • Adrenal Cortex
  • Key Concepts
  • Chapter 44 The Male and Female Reproductive Systems
  • Learning Objectives
  • The Male Reproductive System
  • The Female Reproductive System
  • Mammogenesis and Lactation
  • Menopause
  • Key Concepts
  • Acknowledgment
  • Index