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Dedication to David S. Warner, MD (1953–2021)
1. Brain Metabolism, the Pathophysiology of Brain Injury, and Potential Beneficial Agents and Techniques
Cellular processes that require energy
Nongenomic influences on proteins synthesized: lost in translation
Potential treatments for cerebral ischemia
2. Cerebral and Spinal Cord Blood Flow
PHYSIOLOGY OF THE CEREBRAL CIRCULATION
Therapy for enhancing perfusion
Measurement of cerebral blood flow
VENOUS BLOOD FLOW AND EFFECT ON CBF
FLUID HOMEOSTASIS OF THE CENTRAL NERVOUS SYSTEM
CSF PRODUCTION, COMPOSITION, AND CNS TRANSPORT
NONCHOROIDAL CSF FLUID SECRETION
CSF AND WASTE EGRESS ROUTES FROM THE CNS
4. Effects of Anesthetic Agents and Other Drugs on Cerebral Blood Flow, Metabolism, and Intracranial Pressure
PHYSIOLOGIC AND PHARMACOLOGIC CONSIDERATIONS IN RELATION TO NEUROSURGICAL ANESTHESIA
EFFECTS OF SPECIFIC ANESTHETIC DRUGS AND OTHER DRUGS
5. Modern Neuroradiology Relevant to Anesthetic and Perioperative Management
BASICS OF EVOKED POTENTIALS
SOMATOSENSORY EVOKED POTENTIALS
AUDITORY BRAINSTEM RESPONSES
BASIC ELECTROMYOGRAPHIC MONITORING
ANESTHETIC CONSIDERATIONS DURING MONITORING
7. Transcranial Doppler Ultrasonography in Anesthesia and Neurosurgery
PRINCIPLES OF TRANSCRANIAL DOPPLER ULTRASONOGRAPHY
MEASUREMENTS USING TRANSCRANIAL DOPPLER ULTRASONOGRAPHY
DESCRIBING CEREBRAL HEMODYNAMICS: TESTING AND MONITORING
TRANSCRANIAL DOPPLER ULTRASONOGRAPHY IN CLINICAL PRACTICE
8. Multimodality Neurologic Monitoring
INTRACRANIAL AND CEREBRAL PERFUSION PRESSURES
CEREBRAL BLOOD FLOW MONITORING
CEREBRAL OXYGENATION MONITORING
ELECTROENCEPHALOGRAPHY AND ELECTROCORTICOGRAPHY
MULTIMODALITY NEUROMONITORING
9. Fluid Management During Craniotomy
OSMOLALITY, ONCOTIC PRESSURE, AND INTRAVASCULAR VOLUME
SOLUTIONS FOR INTRAVENOUS USE
FLUID ADMINISTRATION DURING CRANIOTOMY
10. Care of the Acutely Unstable Patient
UTILIZATION OF COGNITIVE AIDS AND EMERGENCY NEUROLOGICAL LIFE SUPPORT PROTOCOLS IN NEUROLOGICAL EMERGENCIES
11. Supratentorial Masses: Anesthetic Considerations
Specific Anesthetic Management
12. Anesthetic Management for Posterior Fossa Surgery
PREOPERATIVE EVALUATION AND PREPARATION
GENERAL MONITORING ISSUES
CHOICE OF PATIENT POSITION
ANESTHETIC CONSIDERATIONS
MAJOR COMPLICATIONS DURING POSTERIOR FOSSA CRANIOTOMY
13. Anesthetic Management of Cerebral Aneurysm Surgery
PREOPERATIVE CONSIDERATIONS
INTRAOPERATIVE CONSIDERATIONS AND INDUCTION OF ANESTHESIA
POSTOPERATIVE CONSIDERATIONS
14. Interventional Neuroradiology Anesthetic Management
PREOPERATIVE PLANNING AND PATIENT PREPARATION
MANAGEMENT OF NEUROLOGIC AND PROCEDURAL CRISES
15. Anesthetic Considerations for Surgical Resection of Brain Arteriovenous Malformations
ETIOLOGY AND PATHOGENESIS
CEREBRAL CIRCULATORY CHANGES IN AVM PATIENTS
PERIOPERATIVE ANESTHETIC MANAGEMENT
OPERATIVE CONSIDERATIONS FOR AVOIDING COMPLICATIONS
16. Occlusive Cerebrovascular Disease: Anesthetic Considerations
PHYSIOLOGIC CONSIDERATIONS
ANATOMICAL CONSIDERATIONS
PROCEDURAL CONSIDERATIONS
17. Awake Craniotomy, Epilepsy, Minimally Invasive, and Robotic Surgery
MINIMALLY INVASIVE CRANIAL NEUROSURGERY
MINIMALLY INVASIVE SPINE SURGERY
18. Stereotactic Neurosurgery: Deep Brain Stimulation, Focused Ultrasound, Therapeutic Radiosurgery, and Biological Therapies
OTHER STEREOTACTIC SURGICAL PROCEDURES
19. The Pituitary Gland and Associated Pathologic States
The Anatomy and Physiology of the Pituitary gland
The Anatomy and Function of the Adult Pituitary Gland
Diseases of the Sellar and Parasellar Regions
20. Perioperative Management of Adult Patients With Severe Traumatic Brain Injury
EPIDEMIOLOGY OF HEAD INJURY
21. Neurosurgical Diseases and Trauma of the Spine and Spinal Cord: Anesthetic Considerations
RADIOLOGIC CONSIDERATIONS
SURGICAL DISORDERS OF THE SPINE
TRAUMA OF THE SPINE AND SPINAL CORD
ANESTHETIC CONSIDERATIONS IN SPINAL SURGERY
22. Postoperative Neurosurgical and Neurocritical Care: Including Head Injury and Multisystem Sequelae
Cardiovascular Management
Neurogenic Pulmonary Edema
Hypoxic Respiratory Failure and Acute Respiratory Distress Syndrome
Fluids, Endocrine, and Electrolyte Abnormalities
23. Anesthesia for Neurosurgery in the Pregnant Patient
MATERNAL PHYSIOLOGIC CHANGES DURING PREGNANCY
EFFECTS OF ANESTHETIC INTERVENTIONS ON UTERINE BLOOD FLOW
UTEROPLACENTAL DRUG TRANSFER AND TERATOGENESIS
MANAGEMENT OF ANESTHESIA FOR CRANIOTOMY DURING PREGNANCY
NEUROAXIAL ANESTHESIA IN PARTURIENTS WITH INTRACRANIAL PATHOLOGY
SPONTANEOUS SPINAL EPIDURAL HEMATOMA
INTERVENTIONAL NEURORADIOLOGY IN PREGNANCY
24. Pediatric Neuroanesthesia and Critical Care
DEVELOPMENTAL CONSIDERATIONS
PREOPERATIVE EVALUATION AND PREPARATION
INTRAOPERATIVE MANAGEMENT
25. Neurologic Disease and Anesthesia
ALZHEIMER’S-TYPE DEMENTIA
AMYOTROPHIC LATERAL SCLEROSIS
GUILLAIN-BARRÉ (ACUTE IDIOPATHIC POLYNEURITIS)
NITROUS OXIDE–INDUCED MYELONEUROPATHY
SARS-COV-2-ASSOCIATED NEUROPSYCHIATRIC SYNDROME
26. Application of Anesthetic Agents in Depression
27. The Management of Pain in the Neurosurgical Patient
ACUTE PAIN MANAGEMENT ASSESSMENT
SYSTEMIC MEDICATIONS FOR ACUTE PAIN MANAGEMENT
REGIONAL ANALGESIC OPTIONS
COMPLICATIONS OF NEUROANESTHESIA PAIN MANAGEMENT
CREATING A CASE-SPECIFIC PAIN MANAGEMENT PLAN
DEFINITION AND TAXONOMY OF PAIN
EVOLUTION OF THE ALGORITHM
ABLATIVE VERSUS AUGMENTATIVE THERAPIES
28. Ethical Considerations in the Care of Patients With Neurosurgical Disease
AN INTRODUCTION TO THE HISTORY AND THEORY OF MEDICAL ETHICS
ISSUES OF CLINICAL DECISION-MAKING
29. Information Management and Technology
SCOPE OF HEALTH INFORMATION TECHNOLOGY
CLINICAL DECISION SUPPORT
CLINICAL AND OPERATIONS RESEARCH
CHALLENGES AND FUTURE DEVELOPMENTS
UNDERSTANDING INFORMATICS HARDWARE
DATA SECURITY AND CONFIDENTIALITY
INFORMATICS RESOURCES AS EDUCATIONAL AND RESEARCH TOOLS
30. Future Advances in Neuroanesthesia
Confidence is ClinicalKey