Chapter 1: Hematopoiesis and Bone Marrow Histology
Chapter 2: Bone Marrow Examination and Techniques
Chapter 3: Synoptic/Integrated Bone Marrow Reporting and Algorithmic Testing
Chapter 4: Overview of Constitutional and Acquired Bone Marrow Disorders
Chapter 5: Overview of Anemia
Chapter 6: Anemias of Inflammation, Chronic Kidney Disease, and Cancer
Chapter 7: Iron Deficiency Anemia
Chapter 8: Autoimmune Hemolytic Anemias
Chapter 9: Alloimmune Hemolytic Anemia and Hemolytic Disease of Newborn
Chapter 10: Microangiopathic Hemolytic Anemia
Chapter 11: Megaloblastic Anemia
Chapter 12: Acquired Nonneoplastic Sideroblastic Anemia
Chapter 13: Alcoholism-Associated Anemia
Chapter 14: Anemia in Older Adults
Chapter 15: Copper Deficiency-Associated Anemia
Chapter 16: Acquired Red Cell Aplasia
Chapter 17: Transient Erythroblastopenia of Childhood
Chapter 18: Parvovirus-Induced Red Cell Aplasia
Chapter 19: Paroxysmal Nocturnal Hemoglobinuria
Chapter 20: Acquired Aplastic Anemia
Chapter 22: Sickle Cell Anemia
Chapter 23: Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency
Chapter 24: Pyruvate Kinase Deficiency
Chapter 25: Hereditary Spherocytosis
Chapter 26: Hereditary Elliptocytosis, Including Hereditary Pyropoikilocytosis
Chapter 27: Diamond-Blackfan Anemia
Chapter 28: Fanconi Anemia
Chapter 29: Congenital Dyserythropoietic Anemia
Chapter 30: Congenital Sideroblastic Anemia
Chapter 31: Congenital Megaloblastic Anemia
SECTION 3: ERYTHROCYTOSIS
Chapter 32: Congenital Erythrocytosis
Chapter 33: Acquired Erythrocytosis
SECTION 4: BENIGN LEUKOCYTE DISORDERS IN BLOOD AND BONE MARROW
Chapter 34: Overview of Benign Leukocyte Disorders in Blood and Bone Marrow
Chapter 41: Lymphocytosis
Chapter 42: Lymphopenia, Constitutional and Acquired
Chapter 43: Plasmacytosis of Bone Marrow
Chapter 44: Hematogones in Bone Marrow
Chapter 45: Lymphoid Aggregates in Bone Marrow
Chapter 46: Granulomas in Bone Marrow
SECTION 5: CONSTITUTIONAL GRANULOCYTIC DISORDERS
CONSTITUTIONAL NEUTROPENIAS
Chapter 47: Severe Congenital Neutropenia and Cyclic Neutropenia
Chapter 48: Shwachman-Diamond Syndrome
Chapter 49: Chediak-Higashi Syndrome
Chapter 50: Myelokathexis in WHIM Syndrome
CONSTITUTIONAL NEUTROPHIL ANOMALIES
Chapter 51: Pelger-Huët Anomaly
Chapter 52: MYH9-Related Disorders
Chapter 53: Selected Lysosomal Storage Diseases With Abnormal Leukocyte Granulation
SECTION 6: MEGAKARYOCYTIC DISORDERS
Chapter 54: Overview of Megakaryocytic Disorders
ACQUIRED PLATELET DISORDERS WITH THROMBOCYTOPENIA
Chapter 55: Immune-Mediated Thrombocytopenia
Chapter 56: Hemolytic Uremic Syndrome
Chapter 57: Heparin-Induced Thrombocytopenia (HIT)
Chapter 58: Thrombotic Thrombocytopenic Purpura
Chapter 59: Pregnancy-Associated Thrombocytopenia
CONSTITUTIONAL PLATELET DISORDERS WITH THROMBOCYTOPENIA
Chapter 60: Thrombocytopenia Absent Radius Syndrome
Chapter 61: Congenital Amegakaryocytic Thrombocytopenia
Chapter 62: Gray Platelet Syndrome
Chapter 63: Wiskott-Aldrich Syndrome-Related Disorders
Chapter 64: Congenital Thrombotic Thrombocytopenic Purpura
Chapter 65: Thrombocytosis
Chapter 66: Overview of Infections
Chapter 67: Hantavirus Pulmonary Syndrome
Chapter 68: Human Immunodeficiency Virus
Chapter 69: Infectious Mononucleosis Syndromes (Epstein-Barr Virus, Cytomegalovirus)
Chapter 70: Parvovirus B19 Infection
Chapter 71: Bacterial Infections, Blood and Bone Marrow Features
Chapter 72: Fungal Infections, Blood and Bone Marrow Features
Chapter 73: Helminthic Infections
Chapter 75: Other Protozoan Infections
Chapter 76: COVID-19 Infection (SARS-CoV-2)
SECTION 8: MISCELLANEOUS NONNEOPLASTIC DISORDERS AND CONDITIONS
Chapter 77: Overview and Classification of Hemophagocytic Disorders in Bone Marrow
Chapter 78: Hematologic Manifestations of Collagen Vascular Disorders
Chapter 79: Hematologic Manifestations of Chronic Kidney Disease
Chapter 80: Lysosomal Storage Diseases With Predominantly Histiocytic Storage
Chapter 81: Homeopathic Remedies and Medications Affecting Blood and Bone Marrow Morphology
Chapter 82: Other Pregnancy-Associated Hematologic Disorders
Chapter 83: VEXAS Syndrome
Chapter 84: Gelatinous Transformation and Other Bone Marrow Stromal Disorders
Chapter 85: Bone Marrow Necrosis
Chapter 86: Crystals in Bone Marrow
Chapter 87: Bone Abnormalities in Bone Marrow Specimens
SECTION 9: MYELOID NEOPLASMS
Chapter 88: Overview and Classification of Myeloid Neoplasms
Chapter 89: Specialized Testing in Myeloid Neoplasms
MYELOPROLIFERATIVE NEOPLASMS
Chapter 90: Overview of Myeloproliferative Neoplasms
Chapter 91: Chronic Myeloid Leukemia
Chapter 92: Chronic Neutrophilic Leukemia
Chapter 93: Polycythemia Vera
Chapter 94: Primary Myelofibrosis
Chapter 95: Essential Thrombocythemia
Chapter 96: Chronic Eosinophilic Leukemia, Not Otherwise Specified
Chapter 97: Myeloproliferative Neoplasm, Unclassifiable
Chapter 98: Systemic Mastocytosis
Chapter 99: Mast Cell Leukemia
MYELOID/LYMPHOID NEOPLASMS WITH EOSINOPHILIA AND TYROSINE KINASE GENE FUSIONS
Chapter 100: Myeloid/Lymphoid Neoplasms With Eosinophilia and PDGFRA
Chapter 101: Myeloid/Lymphoid Neoplasms With Eosinophilia and PDGFRB
Chapter 102: Myeloid/Lymphoid Neoplasms With Eosinophilia and FGFR1
Chapter 103: Myeloid/Lymphoid Neoplasms With Eosinophilia and FLT3 and Other Uncommon Fusion Genes
MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASMS
Chapter 104: Overview of Myelodysplastic/Myeloproliferative Neoplasms
Chapter 105: Chronic Myelomonocytic Leukemia and Precursor Lesions
Chapter 106: Atypical Chronic Myeloid Leukemia
Chapter 107: Myelodysplastic/Myeloproliferative Neoplasm With and Without SF3B1 Mutation and Thrombocytosis
Chapter 108: Myelodysplastic/Myeloproliferative Neoplasms, Not Otherwise Specified, and Provisional Entity
MYELODYSPLASTIC SYNDROMES
Chapter 109: Overview and Classification of Myelodysplastic Syndromes
Chapter 110: Myelodysplastic Syndrome Precursor Lesions
Chapter 111: Myelodysplastic Syndromes With Mutated SF3B1
Chapter 112: Myelodysplastic Syndrome With del(5q)
Chapter 113: Myelodysplastic Syndrome With Multihit TP53 Mutation
Chapter 114: Myelodysplastic Syndromes, Not Otherwise Specified
Chapter 115: Myelodysplastic Syndromes With Excess Blasts
Chapter 116: Myelodysplastic Syndrome/Acute Myeloid Leukemia
Chapter 117: Mimics of Myelodysplasia
HEMATOLOGIC NEOPLASMS WITH GERMLINE PREDISPOSITION, PEDIATRIC MYELODYSPLASTIC SYNDROME, AND JUVENILE MYELOMONOCYTIC LEUKEMIA
Chapter 118: Juvenile Myelomonocytic Leukemia and Similar Neoplasms
Chapter 119: Pediatric Myelodysplastic Syndrome (Refractory Cytopenia of Childhood)
Chapter 120: Hematologic Neoplasms With Germline Predisposition
Chapter 121: Myeloid Proliferations Related to Down Syndrome
Chapter 122: Overview of Acute Myeloid Leukemia
Chapter 123: Acute Promyelocytic Leukemia With t(15;17)(q24.1;q21.2)/PML::RARA
Chapter 124: Acute Promyelocytic Leukemia With Other RARA Rearrangements
Chapter 125: Acute Myeloid Leukemia With t(8;21)(q22;q22.1)/RUNX1::RUNX1T1
Chapter 126: Acute Myeloid Leukemia With inv(16)(p13.1q22) or t(16;16)(p13.1;q22)/CBFB::MYH11
Chapter 127: Acute Myeloid Leukemia With t(9;11)(p21.3;q23.3)/MLLT3::KMT2A and Other KMT2A Rearrangements
Chapter 128: Acute Myeloid Leukemia With Mutated TP53
Chapter 129: Acute Myeloid Leukemia With Uncommon Cytogenetic Abnormalities
Chapter 130: Acute Myeloid Leukemia With Myelodysplasia-Related Gene Mutations or Cytogenetic Abnormalities
Chapter 131: Acute Myeloid Leukemia, Not Otherwise Specified
Chapter 132: Acute Leukemia of Ambiguous Lineage
Chapter 133: Measurable Residual Disease Testing Strategies in Acute Myeloid Leukemia
BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM
Chapter 134: Blastic Plasmacytoid Dendritic Cell Neoplasm
SECTION 10: LYMPHOID NEOPLASMS
Chapter 135: Overview of Lymphoid Neoplasms
Chapter 136: Specialized Testing in Lymphoid Neoplasms
Chapter 137: B-Acute Lymphoblastic Leukemias: Cytogenetic Subtypes and Not Otherwise Specified (ICC)
Chapter 138: B-Acute Lymphoblastic Leukemia, BCR::ABL1-Like
Chapter 139: Novel Genetic Subtypes of B-Acute Lymphoblastic Leukemia
Chapter 140: Measurable Residual Disease Testing Strategies in Acute Lymphoblastic Leukemia
Chapter 141: T- and NK-Cell Acute Lymphoblastic Leukemia (ICC)
Chapter 142: Early T-Cell Precursor Acute Lymphoblastic Leukemia
Chapter 143: Overview and Classification of Mature B-Cell Leukemias, Immunosecretory Neoplasms
Chapter 144: Monoclonal B-Cell Lymphocytosis
Chapter 145: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Chapter 146: B-Cell Prolymphocytic Leukemia
Chapter 147: Splenic Marginal Zone Lymphoma
Chapter 148: Hairy Cell Leukemia
Chapter 149: Splenic B-Cell Leukemia, Hairy Cell Leukemia Variant
Chapter 150: Lymphoplasmacytic Lymphoma
Chapter 151: γ-Heavy Chain Disease
Chapter 152: Monoclonal Gammopathy
Chapter 153: Multiple Myeloma
Chapter 154: Burkitt Lymphoma
Chapter 155: Mantle Cell Lymphoma in Blood and Bone Marrow
Chapter 156: Follicular Lymphoma in Blood and Bone Marrow
Chapter 157: Marginal Zone Lymphoma in Blood and Bone Marrow
Chapter 158: Intravascular Large B-Cell Lymphoma
Chapter 159: Other Large B-Cell Lymphomas in Blood and Bone Marrow
MATURE T-/NK-CELL NEOPLASMS
Chapter 160: Overview and Classification of Mature T-/NK-Cell Neoplasms in Blood and Bone Marrow
Chapter 161: T-Cell Prolymphocytic Leukemia
Chapter 162: T-Cell Large Granular Lymphocytic Leukemia
Chapter 163: Chronic Lymphoproliferative Disorder of NK Cells
Chapter 164: Aggressive NK-Cell Leukemia
Chapter 165: Adult T-Cell Leukemia
Chapter 166: Sézary Syndrome
Chapter 167: Anaplastic Large Cell Lymphoma in Blood and Bone Marrow
Chapter 168: Angioimmunoblastic T-Cell Lymphoma in Blood and Bone Marrow
Chapter 169: Other Mature T-Cell Lymphomas Involving Blood and Bone Marrow
HODGKIN LYMPHOMA IN BONE MARROW
Chapter 170: Classic Hodgkin and Nodular Lymphocyte-Predominant B-Cell Lymphomas in Bone Marrow
SECTION 11: OTHER NEOPLASMS INVOLVING BONE MARROW
Chapter 171: Langerhans Cell Histiocytosis in Bone Marrow
Chapter 172: Posttransplant Lymphoproliferative Disorders in Bone Marrow
Chapter 173: Metastatic Carcinoma and Sarcoma