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Diagnostic Pathology: Endocrine, 3rd Edition

ISBN: 9780323847551
ISBN: 9780323847551
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Διαστάσεις 28 × 22 cm
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Περιγραφή

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of endocrine pathology, it incorporates the most recent clinical, pathologic, and molecular knowledge in this challenging field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Endocrine is a one-stop reference for accurate, complete pathology reports, ideal as a day-to-day reference or as a reliable training resource.
Key Features
    • Provides essential knowledge in all areas of endocrine pathology, including thyroid, parathyroid, pituitary, adrenal, paraganglia, pancreas, skin, neuroendocrine neoplasms, and inherited tumor syndromes—more than 150 diagnoses in all
    • Offers a wealth of new information based on recently recognized and discovered endocrine diseases, as well as tumor types with important implications for patient care
    • Includes new content on thyroid lesions and tumors now associated with DICER1 gene mutations; the correlation of newly characterized genetic abnormalities in endocrine tumors associated with responses to targeted therapies; and newly recognized syndromes, such as multiple endocrine neoplasia type 4 and type 5, glucagon cell hyperplasia and neoplasia, and others
    • Meticulously edited by Dr. Vania Nosé with contributions from renowned pathologists to ensure that common/classic endocrine diagnoses as well as newly recognized diseases and unusual cases, are well covered
    • Features nearly 2,200 high-quality images in print and online, including clinical and histologic images, gross pathology images, radiologic images, and full-color illustrations to help practicing and in-training pathologists reach a confident diagnosis
    • Includes updated criteria, terminology, and classifications for a wide range of tumors according to the latest literature, including the 2022 WHO Endocrine and Neuroendocrine Tumors classification
    • Employs consistently templated chapters, bulleted content, key facts, and annotated images for quick, expert reference at the point of care
    • Includes the enhanced eBook version, which allows you to search all text, figures, and references on a variety of devices
Author Information
By Vania Nosé, MD, PhD, Vania Nosé, MD, PhD, Professor of Pathology, Harvard Medical School, Pathologist & Consultant in Endocrine Pathology, Massachusetts General Hospital, Boston, Massachusetts

Περιεχόμενα

Cover image
Title page
Table of Contents
Copyright
Dedication
Contributing Authors
Preface
Acknowledgments
Sections
SECTION 1: THYROID
List of Tables
NONNEOPLASTIC
HEREDITARY/GENETIC/CONGENITAL
Chapter 1: Thyroglossal Duct Cyst
Key Facts
Key Images
Main Text
Image Gallery
Chapter 2: Ectopic Thyroid
Key Facts
Key Images
Main Text
Image Gallery
Chapter 3: Solid Cell Nests
Key Facts
Key Images
Main Text
Image Gallery
Chapter 4: Dyshormonogenetic Goiter
Key Facts
Key Images
Main Text
Image Gallery
INFECTIOUS
Chapter 5: Acute Thyroiditis
Key Facts
Key Images
Main Text
Image Gallery
AUTOIMMUNE/INFLAMMATORY
Chapter 6: Subacute/Granulomatous Thyroiditis
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 7: Palpation Thyroiditis
Key Facts
Key Images
Main Text
Chapter 8: IgG4-Related Thyroid Disease
Key Facts
Key Images
Main Text
Image Gallery
Chapter 9: Riedel Thyroiditis
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 10: Hashimoto Thyroiditis
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 11: Graves Disease (Diffuse Hyperplasia)
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 12: Amyloid Goiter
Key Facts
Key Images
Main Text
Image Gallery
REACTIVE
Chapter 13: Pigments and Crystals, Thyroid
Key Facts
Key Images
Main Text
Image Gallery
Chapter 14: Post-FNA Site Changes, Thyroid
Key Facts
Key Images
Main Text
Image Gallery
NEOPLASTIC
FOLLICULAR CELL-DERIVED NEOPLASMS
Chapter 15: Thyroid Follicular Nodular Disease
Key Facts
Key Images
Main Text
Image Gallery
Chapter 16: Adenomatous Nodules
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 17: Follicular Thyroid Adenoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 18: Follicular Thyroid Adenoma With Papillary Architecture
Key Facts
Key Images
Main Text
Image Gallery
Chapter 19: Oncocytic Thyroid Adenoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 20: Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclear Features
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 21: Hyalinizing Trabecular Tumor of Thyroid
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 22: Follicular Thyroid Carcinoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 23: Oncocytic Thyroid Carcinoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 24: Invasive Encapsulated Follicular Variant Papillary Thyroid Carcinoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 25: Kinase Fusion-Related Thyroid Carcinomas
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 26: Follicular Cell-Derived Thyroid Carcinoma, High Grade
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 27: Anaplastic Thyroid Carcinoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 28: Papillary Thyroid Carcinoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 29: Classic Papillary Thyroid Carcinoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 30: Infiltrative Follicular Variant Papillary Thyroid Carcinoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 31: Macrofollicular Papillary Thyroid Carcinoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 32: Diffuse Sclerosing Papillary Thyroid Carcinoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 33: Oncocytic Papillary Thyroid Carcinoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 34: Tall Cell Papillary Thyroid Carcinoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 35: Columnar Cell Papillary Thyroid Carcinoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 36: Clear Cell Papillary Thyroid Carcinoma
Key Facts
Key Images
Main Text
Chapter 37: Solid/Trabecular Papillary Thyroid Carcinoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 38: Hobnail Papillary Thyroid Carcinoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 39: Warthin-Like Papillary Thyroid Carcinoma
Key Facts
Key Images
Main Text
Image Gallery
C-CELL-DERIVED TUMORS
Chapter 40: C-Cell Hyperplasia
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 41: Medullary Thyroid Carcinoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
MIXED MEDULLARY AND FOLLICULAR CELL CARCINOMA
Chapter 42: Mixed Medullary and Follicular Cell-Derived Thyroid Carcinoma
Key Facts
Key Images
Main Text
Image Gallery
THYMIC TUMORS WITHIN THYROID
Chapter 43: Spindle Epithelial Tumor With Thymus-Like Differentiation
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 44: Intrathyroid Thymic Carcinoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
SALIVARY GLAND-LIKE THYROID TUMORS
Chapter 45: Mucoepidermoid Carcinoma of Thyroid
Key Facts
Key Images
Main Text
Image Gallery
Chapter 46: Secretory Carcinoma of Salivary Gland Type
Key Facts
Key Images
Main Text
Image Gallery
HEMATOLYMPHOID TUMORS
Chapter 47: Lymphoma, Thyroid
Key Facts
Key Images
Main Text
Image Gallery
Chapter 48: Follicular Dendritic Cell Sarcoma, Thyroid
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 49: Langerhans Cell Histiocytosis, Thyroid
Key Facts
Key Images
Main Text
Image Gallery
GERM CELL ORIGIN
Chapter 50: Benign Thyroid Teratoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 51: Struma Ovarii, Struma Carcinoid, and Malignant Struma Ovarii
Key Facts
Key Images
Main Text
Image Gallery
EMBRYONAL THYROID TUMORS
Chapter 52: Thyroblastoma
Key Facts
Key Images
Main Text
Image Gallery
MESENCHYMAL AND STROMAL TUMORS
Chapter 53: Peripheral Nerve Sheath Tumor, Thyroid
Key Facts
Key Images
Main Text
Image Gallery
Chapter 54: Solitary Fibrous Tumor, Thyroid
Key Facts
Key Images
Main Text
Image Gallery
Chapter 55: Paraganglioma, Thyroid
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 56: Leiomyoma and Leiomyosarcoma, Thyroid
Key Facts
Key Images
Main Text
Image Gallery
Chapter 57: Angiosarcoma, Thyroid
Key Facts
Key Images
Main Text
Image Gallery
Chapter 58: Primary Ewing Sarcoma, Thyroid
Key Facts
Key Images
Main Text
Image Gallery
SECONDARY TUMORS WITHIN THYROID
Chapter 59: Metastasis to Thyroid Gland
Key Facts
Key Images
Main Text
Image Gallery
TUMORS OF UNCERTAIN HISTOGENESIS
Chapter 60: Cribriform Morular Thyroid Carcinoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 61: Sclerosing Mucoepidermoid Carcinoma With Eosinophilia
Key Facts
Key Images
Main Text
Tables
Image Gallery
MOLECULAR PATHOLOGY OF THYROID NEOPLASMS
Chapter 62: Molecular Pathology of Thyroid Neoplasms
Main Text
Tables
Image Gallery
PROTOCOL FOR EXAMINATION OF SPECIMENS FROM PATIENTS WITH CARCINOMA OF THYROID GLAND
Chapter 63: Thyroid Carcinoma Protocol
Key Facts
Key Images
Main Text
SECTION 2: PARATHYROID GLAND
NONNEOPLASTIC
Chapter 64: Primary Multiglandular Parathyroid Disease
Key Facts
Key Images
Main Text
Image Gallery
Chapter 65: Primary Parathyroid Clear Cell Hyperplasia
Key Facts
Key Images
Main Text
Image Gallery
Chapter 66: Secondary Parathyroid Hyperplasia
Key Facts
Key Images
Main Text
Image Gallery
Chapter 67: Tertiary Parathyroid Hyperplasia
Key Facts
Key Images
Main Text
Image Gallery
Chapter 68: Chronic Parathyroiditis
Key Facts
Key Images
Main Text
Image Gallery
NEOPLASTIC
Chapter 69: Parathyroid Adenoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 70: Parathyroid Lipoadenoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 71: Atypical Parathyroid Tumor
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 72: Parathyroid Carcinoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 73: Metastasis to Parathyroid Gland
Key Facts
Key Images
Main Text
Tables
Image Gallery
SECTION 3: ADRENAL GLANDS
ADRENAL CORTICAL NONNEOPLASTIC
Chapter 74: Adrenal Heterotopia
Key Facts
Key Images
Main Text
Image Gallery
Chapter 75: Adrenal Hypoplasia and Malformations
Key Facts
Key Images
Main Text
Image Gallery
Chapter 76: Adrenal Cytomegaly
Key Facts
Key Images
Main Text
Tables
Chapter 77: Infectious Disorders, Adrenal Glands
Key Facts
Key Images
Main Text
Image Gallery
Chapter 78: Autoimmune Adrenalitis
Key Facts
Key Images
Main Text
Chapter 79: Adrenal Amyloidosis
Key Facts
Key Images
Main Text
Image Gallery
Chapter 80: Incidental Adrenal Nodules
Key Facts
Key Images
Main Text
Image Gallery
Chapter 81: Adrenal Cysts
Key Facts
Key Images
Main Text
Image Gallery
ADRENAL CORTICAL NEOPLASTIC
Chapter 82: Adrenocortical Hyperplasia and Adrenocortical Nodular Disease
Key Facts
Key Images
Main Text
Image Gallery
Chapter 83: Primary Pigmented Nodular Adrenocortical Disease
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 84: Nonfunctioning Adrenal Cortical Adenoma
Key Facts
Key Images
Main Text
Chapter 85: Aldosterone-Producing Adenoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 86: Cortisol-Secreting Adrenal Cortical Adenoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 87: Sex Hormone-Producing Adrenal Cortical Adenoma
Key Facts
Key Images
Main Text
Chapter 88: Oncocytic Adrenal Cortical Adenoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 89: Adrenal Cortical Carcinoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 90: Adrenal Cortical Neoplasms in Children
Key Facts
Key Images
Main Text
Tables
Image Gallery
ADRENAL MEDULLA AND PARAGANGLIA
Chapter 91: Adrenal Medullary Hyperplasia
Key Facts
Key Images
Main Text
Image Gallery
Chapter 92: Pheochromocytoma and Paraganglioma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 93: Composite Pheochromocytoma and Composite Paraganglioma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 94: Neuroblastic Tumors of Adrenal Gland
Key Facts
Key Images
Main Text
Tables
Image Gallery
ADRENAL MESENCHYMAL AND STROMAL TUMORS
Chapter 95: Primary Adrenal Myelolipoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 96: Primary Adrenal Melanoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 97: Primary Adrenal Benign Connective Tissue Tumor
Key Facts
Key Images
Main Text
Chapter 98: Primary Adrenal Angiosarcoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 99: Primary Adrenal Leiomyosarcoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 100: Metastasis to Adrenal Gland
Key Facts
Key Images
Main Text
Tables
Image Gallery
PROTOCOL FOR EXAMINATION OF SPECIMENS FROM PATIENTS WITH CARCINOMA OF ADRENAL GLAND
Chapter 101: Adrenal Cortical Carcinoma Protocol
Key Facts
Key Images
Main Text
SECTION 4: PITUITARY GLAND
NONNEOPLASTIC
Chapter 102: Hypophysitis, Pituitary Gland
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 103: Hyperplasia, Pituitary Gland
Key Facts
Key Images
Main Text
Chapter 104: Sarcoidosis, Pituitary Gland
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 105: Infarction, Pituitary Gland
Key Facts
Key Images
Main Text
Chapter 106: Sheehan Syndrome, Pituitary Gland
Key Facts
Key Images
Main Text
Chapter 107: Cystic Lesions of Sellar Region
Key Facts
Key Images
Main Text
Image Gallery
NEOPLASTIC
ANTERIOR NEUROENDOCRINE NEOPLASMS
Chapter 108: Empty Sella Syndrome
Key Facts
Key Images
Main Text
Chapter 109: Pituitary Neuroendocrine Tumor/Adenoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 110: Somatotroph PitNET/Adenoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 111: Lactotroph PitNET/Adenoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 112: Thyrotroph PitNET/Adenoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 113: Plurihormonal PitNET/Adenoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 114: Corticotroph PitNET/Adenoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 115: Gonadotroph PitNET/Adenoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 116: Null Cell PitNET/Adenoma
Key Facts
Key Images
Main Text
Chapter 117: Metastatic Pituitary Neuroendocrine Tumor
Key Facts
Key Images
Main Text
Image Gallery
OTHER ANTERIOR PITUITARY TUMORS
Chapter 118: Adamantinomatous Craniopharyngioma
Key Facts
Key Images
Main Text
Chapter 119: Papillary Craniopharyngioma
Key Facts
Key Images
Main Text
Chapter 120: Pituitary Blastoma
Key Facts
Key Images
Main Text
Image Gallery
POSTERIOR PITUITARY NEOPLASMS
Chapter 121: Pituicytoma, Spindle Cell Oncocytoma, and Granular Cell Tumor of Sella
Key Facts
Key Images
Main Text
Image Gallery
NEURONAL TUMORS
Chapter 122: Gangliocytoma
Key Facts
Key Images
Main Text
Image Gallery
Chapter 123: Neuronal Cell Tumors, Pituitary
Key Facts
Key Images
Main Text
OTHER PITUITARY TUMORS
Chapter 124: Metastasis to Pituitary Gland
Key Facts
Key Images
Main Text
Chapter 125: Mesenchymal and Hematopoietic Tumors, Pituitary Gland
Key Facts
Key Images
Main Text
Image Gallery
PROTOCOL FOR EXAMINATION OF SPECIMENS FROM PATIENTS WITH PRIMARY PITUITARY TUMORS
Chapter 126: Protocol for Examination of Specimens From Patients With Primary Pituitary Tumors
Main Text
Image Gallery
SECTION 5: ENDOCRINE PANCREAS
Chapter 127: Pancreatic Neuroendocrine Neoplasms
Key Facts
Key Images
Main Text
Tables
Image Gallery
PROTOCOL FOR EXAMINATION OF SPECIMENS FROM PATIENTS WITH CARCINOMA OF ENDOCRINE PANCREAS
Chapter 128: Pancreatic Neuroendocrine Carcinoma Protocol
Key Facts
Key Images
Main Text
SECTION 6: ENDOCRINE SKIN
Chapter 129: Merkel Cell Carcinoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
SECTION 7: FAMILIAL TUMOR SYNDROMES
MAJOR ENDOCRINE GLAND AFFECTED
THYROID GLAND
Chapter 130: DICER1 Syndrome
Main Text
Tables
Image Gallery
Chapter 131: Familial Thyroid Carcinoma
Main Text
Image Gallery
Chapter 132: McCune-Albright Syndrome
Main Text
Image Gallery
Chapter 133: Multiple Endocrine Neoplasia Type 2 (MEN2)
Main Text
Tables
Image Gallery
Chapter 134: Nonsyndromic Familial Follicular Cell-Derived Thyroid Carcinoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
Chapter 135: PTEN Hamartoma Tumor Syndromes
Main Text
Image Gallery
Chapter 136: Syndromic Familial Follicular Cell-Derived Thyroid Carcinoma
Key Facts
Key Images
Main Text
Tables
Image Gallery
PARATHYROID GLAND
Chapter 137: Familial Isolated Hyperparathyroidism
Main Text
Tables
Image Gallery
Chapter 138: Hyperparathyroidism-Jaw Tumor Syndrome
Main Text
Image Gallery
Chapter 139: Multiple Endocrine Neoplasia Type 1 (MEN1)
Main Text
Tables
Image Gallery
Chapter 140: Multiple Endocrine Neoplasia Type 4 (MEN4)
Main Text
Tables
Image Gallery
ADRENAL GLAND AND PARAGANGLIA
Chapter 141: Beckwith-Wiedemann Syndrome
Main Text
Tables
Image Gallery
Chapter 142: Carney Complex
Main Text
Tables
Image Gallery
Chapter 143: Hereditary Neuroblastoma
Main Text
Image Gallery
Chapter 144: Hereditary Paraganglioma/Pheochromocytoma Syndromes
Main Text
Tables
Image Gallery
Chapter 145: Multiple Endocrine Neoplasia Type 5, MAX-Related
Main Text
Image Gallery
Chapter 146: Neurofibromatosis Type 1
Main Text
Image Gallery
Chapter 147: von Hippel-Lindau Syndrome
Main Text
Image Gallery
Chapter 148: SDH-Deficient Pheochromocytoma and Paraganglioma
Main Text
Tables
Image Gallery
PANCREAS
Chapter 149: Glucagon Cell Hyperplasia and Neoplasia
Main Text
Image Gallery
Chapter 150: Hereditary and Familial Pancreatic Cancer Syndrome
Main Text
Tables
Image Gallery
Chapter 151: MAFA-Related Familial Insulinomatosis
Main Text
Image Gallery
Chapter 152: Pancreatic Neuroendocrine Tumor Syndromes
Main Text
Tables
Image Gallery
SECTION 8: PARANEOPLASTIC SYNDROMES
Chapter 153: Ectopic (Paraneoplastic) Syndromes
Key Facts
Key Images
Main Text
Tables
Image Gallery
INDEX