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Male Infertility, 1st Edition Management of Infertile Men in Reproductive Medicine

ISBN: 9780323930475
Εκδόσεις:
Διαστάσεις 24 × 19 cm
Μορφή

Paperback

Εκδόσεις

Ημ. Έκδοσης

2024/03

Σελίδες

432

Έκδοση

1η έκδοση

Κύριος Συγγραφέας

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112,00€(Περιλαμβάνεται ΦΠΑ 6%)

Διαθεσιμότητα: 11-14 ημέρες

Περιγραφή

Despite the fact that about half of infertility problems stem from male factors, gynecologists are often the first health care providers to perform the initial assessment of the infertile couple. For this reason, it is critical that gynecologists and reproductive medicine specialists remain up to date on the primary conditions that cause male infertility, as well as current diagnostic tools and treatment options of both natural and assisted conception. From diagnosis through treatment, Male Infertility: Management of Infertile Men in Reproductive Medicine offers expert, straightforward guidance on the pathophysiology and management of male infertility for clinicians who assist couples early in the process of trying to conceive.
Key Features
  • Covers diagnostic aspects of male infertility (clinical, laboratory, and imaging methods) as well as various therapeutic options including classical and advanced surgical procedures.
  • Discusses intrauterine insemination, conventional in vitro fertilization, intracytoplasmic sperm injection, sperm cryopreservation, preimplantation genetic testing, and more.
  • Begins each chapter with key points and ends with clinical scenarios of real-life problems and their solutions.
  • Shares the knowledge and expertise of global experts in the field.
  • An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Any additional digital ancillary content may publish up to 6 weeks following the publication date.

Περιεχόμενα

  • Cover image
  • Title page
  • Table of Contents
  • Copyright
  • Dedication
  • Contributors
  • Foreword
  • Preface
  • About the Author
  •     List of Illustrations
  •     List of Tables
  • SECTION 1. Definition, Epidemiology, and Implications of Male Infertility
  • 1.  Definition, epidemiology, and implications of male infertility
  •     Introduction
  •     Epidemiology of male infertility
  •     Health implications of male infertility
  •     Summary
  •     References
  • SECTION 2. Causes of Male Infertility
  • 2.  Pretesticular causes of male infertility
  •     Introduction
  •     Physiopathology of the hypothalamic-pituitary-gonadal axis
  •     Clinical picture and diagnosis
  •     Etiologies of hypogonadotropic hypogonadism
  •     Medical treatment of hypogonadotropic hypogonadism
  •     Clinical case scenarios
  •     Summary
  •     References
  • 3.  Testicular causes of male infertility
  •     Introduction
  •     Congenital causes of male infertility
  •     Genetic causes
  •     Infective causes
  •     Disorders of spermatogenesis
  •     Testicular tumors
  •     Trauma to the testis
  •     Torsion of the testis
  •     Testicular microcalcifications
  •     Cell phone radiation
  •     Heat exposure
  •     Secondary testicular causes of male infertility
  •     Management of testicular causes of male infertility
  •     Treatment
  •     Clinical case scenarios
  •     Summary
  •     References
  • 4.  Posttesticular causes of male infertility
  •     Introduction
  •     Posttesticular causes of male infertility
  •     Clinical scenarios
  •     Summary
  •     References
  • 5.  Environmental/lifestyle factors and male infertility
  •     Introduction
  •     Environmental/occupational factors and male infertility
  •     Summary
  •     References
  • 6.  Idiopathic male infertility
  •     Introduction
  •     Etiology and prevailing theories
  •     Diagnosis of idiopathic male infertility
  •     Treatment of idiopathic male infertility
  •     Summary
  •     References
  • SECTION 3. Diagnosis of Male Infertility
  • 7.  Medical history and physical examination of infertile males
  •     Introduction
  •     History
  •     Physical examination
  •     Telehealth and male infertility assessment
  •     Summary
  •     References
  • 8.  Basic semen analysis
  •     Introduction
  •     Basic semen examination—changes in the world health organization manual, 6th edition
  •     Reference values
  •     Conclusion
  •     Summary
  •     References
  • 9.  Sperm DNA fragmentation tests
  •     Introduction
  •     Sperm DNA structure
  •     Types of sperm DNA fragmentation
  •     DNA repair
  •     Causes of sperm DNA fragmentation
  •     Impact of SDF on reproductive outcomes
  •     Terminal deoxynucleotidyl transferase dUTP nick-end labeling assay
  •     Sperm chromatin structure assay
  •     Sperm chromatin dispersion test
  •     Comet assay (single-cell gel electrophoresis)
  •     Current recommendations of sperm DNA fragmentation testing by professional societies
  •     Challenges of sperm DNA fragmentation testing in clinical practice
  •     Clinical scenarios
  •     Summary
  •     References
  • 10.  Genetic and genomic tests of infertile males
  •     Introduction
  •     Genetic tests
  •     Genomic tests
  •     Clinical/laboratory scenarios
  •     Summary
  •     Funding
  •     References
  • 11.  Computer-assisted semen analysis
  •     Introduction
  •     Description of different types of computed-assisted semen analysis systems
  •     Semen examinations using computer-assisted semen analysis
  •     Recommendations, advantages, and disadvantages of computer-assisted semen analysis systems
  •     Perspectives and emerging technologies
  •     Summary
  •     References
  • 12.  Seminal oxidative stress and reactive oxygen species testing
  •     Introduction
  •     Sources of reactive oxygen species in the male reproductive tract
  •     Antioxidant regulation of reactive oxygen species in the male reproductive tract
  •     Physiological role of reactive oxygen species in male reproduction and fertility
  •     Pathological effects of oxidative stress in male reproduction
  •     Seminal biomarkers of reactive oxygen species and oxidative stress
  •     Summary
  •     References
  • 13.  Assessment of reproductive hormones in infertile males
  •     Introduction
  •     Gonadotropins
  •     Testosterone and testicular androgens
  •     The human spermatogenesis
  •     Pretesticular causes: The hypothalamus-pituitary-gonadal axis
  •     Testicular causes: Primary testicular failure
  •     Laboratory assessment
  •     Clinical case scenarios
  •     Summary
  •     References
  • 14.  Imaging in male factor infertility
  •     Introduction
  •     Male reproductive gross anatomy
  •     Basic principles of ultrasonography
  •     Basic principles of computed tomography
  •     Basic principles of magnetic resonance imaging
  •     Testis imaging
  •     Epididymis imaging
  •     Vas deferens imaging
  •     Seminal vesicle and ejaculatory duct imaging
  •     Summary
  •     References
  • SECTION 4. Medical Treatment of Male Infertility
  • 15.  Hormonal therapy of male infertility
  •     Introduction
  •     Hormonal therapy of infertile males
  •     Clinical case scenarios
  •     Summary
  •     References
  • 16.  Antioxidants therapy of male infertility
  •     Introduction
  •     Protective action of antioxidants
  •     Impact of antioxidant therapy of infertile males on semen parameters
  •     Impact of antioxidant therapy of infertile males on pregnancy outcomes
  •     Practice patterns of the use of antioxidant therapy in male infertility
  •     Professional societies’ guidelines of antioxidant therapy in male infertility
  •     Limitations of antioxidant therapy in male infertility
  •     Summary
  •     References
  • 17.  Antibiotic therapy of male infertility
  •     Introduction
  •     Semen and testicular microbiomes
  •     Seminal microbiome and assisted reproductive technique outcome
  •     Diagnosis of genital tract infection
  •     Impact of leukocytospermia on male fertility
  •     Antibiotics therapy of male infertility
  •     Overview of the current guidelines
  •     Antibiotics as adjuvants in assisted reproductive technique
  •     Clinical case scenarios
  •     Antibiotic alternatives
  •     Summary
  •     References
  • 18.  Alternative therapy of male infertility
  •     Introduction
  •     Nutrition and male fertility
  •     Malnutrition/nutrient deficiencies and male infertility
  •     Herbal treatment for male infertility
  •     Herbs with positive effects on sperm quality
  •     Herbs with negative effects on sperm quality
  •     Physical exercise and male fertility
  •     The positive impact of exercise on male fertility
  •     The negative impact of exercise on male fertility
  •     Psychological and behavioral therapy
  •     Effects of psychological stress on reproductive function
  •     Treatment of psychological stress–related disease
  •     Clinical/laboratory case scenario
  •     Summary
  •     References
  • SECTION 5. Surgical Treatment of Male Infertility
  • 19.  Varicocele repair in infertile males
  •     Introduction
  •     Pathogenesis of varicocele
  •     Diagnosis and grading of varicocele
  •     Impact of varicocele on male fertility
  •     Society guidelines
  •     Types of intervention
  •     Outcomes of intervention
  •     Complications of varicocelectomy
  •     Summary
  •     Clinical case scenarios
  •     References
  • 20.  Management of ejaculatory duct obstruction
  •     Introduction
  •     Epidemiology of obstruction of male reproductive tract
  •     Anatomical considerations
  •     Functional considerations
  •     Etiology and pathophysiology of ejaculatory duct obstruction
  •     Evaluation of ejaculatory duct obstruction
  •     Differential diagnosis of ejaculatory duct obstruction
  •     Treatment of ejaculatory duct obstruction
  •     Clinical case scenario
  •     Summary
  •     References
  • 21.  Surgical sperm retrieval and processing for assisted reproductive technology
  •     Introduction
  •     Narrative review
  •     Summary
  •     References
  • SECTION 6. Assisted Reproduction
  • 22.  Intrauterine insemination with homologous semen
  •     Introduction
  •     Diagnostic work-up before intrauterine insemination and when to start with intrauterine insemination
  •     Indications for intrauterine insemination with partner semen
  •     Factors influencing intrauterine insemination outcome
  •     Perinatal outcome after intrauterine insemination/prevention of multiple pregnancies
  •     Cost effectiveness of intrauterine insemination
  •     Summary
  •     References
  • 23.  In vitro fertilization/intracytoplasmic sperm injection
  •     Introduction
  •     Indications for in vitro fertilization
  •     Current technique of in vitro fertilization
  •     Improvements in in vitro fertilization techniques over the past 30 years
  •     Advances of intracytoplasmic sperm injection—improvements over the last 30 years
  •     Clinical case scenarios
  •     Summary
  •     References
  • 24.  Techniques for selection of surgically retrieved sp erm for intracytoplasmic sperm injection
  •     Introduction
  •     Surgically retrieved sperm selection
  •     Sperm selection methods
  •     Intracytoplasmic morphologically selected sperm injection
  •     Microfluidics-based sperm selection techniques
  •     Clinical case scenarios
  •     Summary
  •     References
  • 25.  Sperm banking
  •     Introduction
  •     Indications of sperm cryopreservation
  •     Sperm cryopreservation
  •     Assisted reproductive technique outcomes with frozen donor sperm
  •     Emergence of field of oncofertility and its importance in assisted reproductive technique
  •     Management of cryobanking services and facilities
  •     General requirements for sperm banking
  •     Conclusions
  •     Summary
  •     References
  • SECTION 7. Clinical Practice Guidelines for Male Infertility
  • 26.  Guidelines of the American society for reproductive medicine, American urological association, and European association of urology
  •     Introduction
  •     Causes and risk factors of male infertility
  •     Diagnosis of male infertility
  •     Management of male infertility before the assisted reproductive technology stage
  •     Male infertility management with assisted reproductive techniques
  •     Clinical/laboratory case scenario
  •     Summary
  •     References
  • 27.  Expert opinion: Management of male infertility in the postintracytoplasmic sperm injection era
  •     Introduction
  •     The importance of evaluating and treating male infertility
  •     Controversies in evaluation of an infertile male
  •     Conclusion
  •     Summary
  •     References
  • SECTION 8. Insights Into the Future of Male Infertility
  • 28.  Clinical perspective in the postintracyoplasmic sperm injection era
  •     Introduction
  •     Role of epigenetics in the management of male infertility
  •     Role of proteomics in the management of male infertility
  •     Optimizing sperm selection techniques for intracytoplasmic sperm injection
  •     Molecular markers for predicting sperm retrieval in nonobstructive azoospermia
  •     The future of stem cell therapy in male infertility
  •     Fertility preservation in cancer patients
  •     Role of artificial intelligence in the practice of male infertility
  •     Summary
  •     References
  • 29.  Research perspectives in the postintracytoplasmic sperm injection era
  •     Introduction
  •     New developments in androurological diagnostics
  •     Utility of artificial intelligence in reproductive medicine
  •     Applications of stem cell research in male fertility preservation
  •     Summary
  •     References
  • Index