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Manual of Hematopoietic Cell Transplantation and Cellular Therapies, 1st Edition

ISBN: 9780323798334
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Διαστάσεις 28 × 22 cm
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Περιγραφή

Led by authors from MD Anderson’s Stem Cell Transplantation and Cellular Therapy Department, the world’s largest and highly respected program at the forefront of rapidly advancing treatments in the field, Manual of Hematopoietic Cell Transplantation and Cellular Therapies is a comprehensive, focused reference covering the latest clinical developments and applications of stem cell transplant and cellular therapies for hematologic malignancies and solid tumors. This cutting-edge title, with a majority contribution from the MD Anderson Cancer Center and leading faculty from other academic institutions, covers breakthrough cell-based therapies for various diseases including lymphoma, multiple myeloma, leukemia, and select solid tumor and autoimmune diseases. This unique, definitive resource is essential for hematologists, fellows in hematology and immunotherapy, mid-level providers, pharmacists, and oncologists who refer patients for cell-based therapies.
Key Features
  • Addresses hematologic conditions including leukemia, lymphoma, and myeloma.
  • Offers guidance on hematopoietic cell transplantation for solid tumors.
  • Covers basic science principles, clinical aspects, pharmacology, radiation therapy, and disease-specific guidelines, including prevention and management of complications.
  • Discusses key topics such as hematopoietic cell collection, bone marrow harvesting, umbilical cord blood transplantation, CAR T-cell therapy, and patient/donor selection and preparation of HCT.
  • Features extensive summary boxes, bulleted content, and algorithms throughout for quick and easy reference.
  • Offers team-based, clinically-focused coverage from world-renowned leaders in the field.
  • An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
Author Information
Edited by Qaiser Bashir, MD, Associate Professor of Medicine, Department of Stem Cell Transplantation & Cellular Therapy, University of Texas MD Anderson Cancer Center, Houston, Texas; Elizabeth J. Shpall, MD, Professor and Chair, at interim, Department of Stem Cell Transplantation and Cellular Therapy, Division of Cancer Medicine Director, Cell Therapy Laboratory, Director, Cord Blood Bank, The University of Texas MD Anderson Cancer Center, Houston, Texas and Richard E. Champlin, MD, Professor, Department of Stem Cell Transplantation and Cellular Therapy, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas

Περιεχόμενα

PART I: Introduction and Biological Aspects

1. Hematopoietic Transplantation: Past, Present, and Future

2. Role of the Human Leukocyte Antigen System in Hematopoietic Stem Cell Transplantation
PART II: Methodology

3. Hematopoietic Cell Collection

4. Bayesian Statistical Methods in Stem Cell Transplantation and Cellular Therapy
PART III: General Clinical Aspects

5. Patient and Donor Assessments in Preparation for Transplant

6. Transfusion Support During Hematopoietic Cell Transplantation

7. Haploidentical Hematopoietic Cell Transplantation

8. Umbilical Cord Blood Transplantation

9. Process and General Management of Patients Undergoing Chimeric Antigen Receptor Therapies
PART IV: Pharmacology and Radiation Therapy

10. Preparative Regimens Used in Hematopoietic Cell Transplantation and Chimeric Antigen Receptor T-Cell Therapies

11. Pharmacology of Drugs Used in Hematopoietic Cell Transplant and Chimeric Antigen Receptor Therapies

12. Radiobiologic Principles and the Role of Radiotherapy in Hematopoietic Cell Transplant and Chimeric Antigen Receptor T-Cell Therapy
PART V: Disease-Specific Indications and Results

13. Hematopoietic Cell Transplantation in Adult With Acute Myeloid Leukemia

14. Chimeric Antigen Receptor Therapy in Acute Myeloid Leukemia

15. Allogeneic Hematopoietic Cell Transplantation for Patients With Acute Lymphoblastic Leukemia

16. Chimeric Antigen Receptor T-Cell Therapy in Acute Lymphoblastic Leukemia

17. Hematopoietic Cell Transplantation and Other Cellular Therapies for Chronic Lymphocytic Leukemia

18. Allogeneic Hematopoietic Cell Transplantation in Myelodysplastic Syndrome Patients

19. Allogeneic Cell Transplantation for Myeloproliferative Neoplasms

20. Hematopoietic Cell Transplantation in Aplastic Anemia

21. Hematopoietic Cell Transplantation in Multiple Myeloma

22. Chimeric Antigen Receptor Therapy in Multiple Myeloma

23. Hematopoietic Cell Transplantation in Light Chain Amyloidosis

24. Hematopoietic Cell Transplantation for Non-Hodgkin Lymphoma

25. Hematopoietic Cell Transplantation for Hodgkin Lymphoma

26. Chimeric Antigen Receptor Therapy in Lymphoma

27. Hematopoietic Cell Transplantation in Rare Hematologic Malignancies

28. Hematopoietic Cell Transplantation for Germ-Cell Tumors and Other Adult Solid Tumors

29. Natural Killer Cells: A Promising Cellular Therapy Platform to Conquer Cancer
PART VI: Prevention and Management of Complications

30. Infection Control, Prophylaxis, and Vaccinations in Hematopoietic Cell Transplantation Recipients

31. Management of Infections in Stem Cell Transplant Recipients

32. Graft Failure After Hematopoietic Cell Transplantation

33. Graft-Versus-Host Disease

34. Miscellaneous Complications of Hematopoietic Cellular Transplantation

35. Cytokine Release Syndrome Following CD19 Directed Chimeric Antigen Receptor T-Cell Therapy

36. Neurologic Complications of Chimeric Antigen Receptor Therapy

37. Miscellaneous Complications of Chimeric Antigen Receptor T-Cell Therapy

38. Symptom Management and Palliative Care in Hematologic Malignancies

39. Survivorship
Index