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Manual of Surgical Pathology, 4th Edition

ISBN: 9780323546324
ISBN: 9780323546324
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Περιγραφή

Offering complete, practical guidance on the evaluation of the surgical pathology specimen, Manual of Surgical Pathology encapsulates the standard operating procedures at Brigham and Women’s Hospital, one of the busiest and most respected pathology departments in the world. From a specimen’s arrival in the department to preparation of the final report, you’ll find step-by-step instructions on specimen processing, tissue handling, gross dissection technique, histological examination, application of special stains, development of a differential diagnosis, and more. The fully revised 4th Edition is an invaluable reference for residents, practicing pathologists, and pathology assistants as a practical, everyday resource for learning proper procedure as well as an excellent guide for board review.
Key Features
    • Helps you find information quickly with a user-friendly design, concise paragraphs, numbered lists, and bulleted material throughout the text.
    • Reflects the latest AJCC staging information, as well as updates throughout on reporting procedures, protocols, and safety.
    • Offers detailed instructions on the dissection, description, and sampling of specimens, and explains the application of pathology reports to patient management.
    • Provides procedures for new types of specimens including pulmonary image guided resections, endoscopic mucosal resection, endoscopic submucosal dissection, laparoscopic hysterectomy, or nephrectomy morcellation, vertical sleeve gastrectomy, and evaluation of breast implant capsules with a clinical suspicion of lymphoma
    • Features dozens of illustrations that demonstrate the gross appearance of common pathologic lesions, and more than 150 tables that examine the interpretation of histochemical stains, immunohistochemical studies, electron microscopy findings, cytogenetic changes, and much more.
    • Examines the specimens from every organ and system as well as bullets, medical devices, and foreign materials.
    • Includes a new chapter on occupational hazards for pathologists ranging from visual and musculoskeletal problems to exposure and prevention of workplace acquired infection and cancer.
    • Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Author Information
By Susan C. Lester, MD, PhD, Associate Pathologist, Former Chief of Breast Pathology Services, Brigham and Women’s Hospital, Assistant Professor, Harvard Medical School, Boston, Massachusetts

Περιεχόμενα

Cover Image
Title Page
Copyright
Preface to the First Edition
Preface to the Second Edition
Preface to the Third Edition
Preface to the Fourth Edition
Acknowledgments
Consultants
Table of Contents
Part One
Chapter 1 Requests for Pathologic Evaluation
Patient Identification
Identification of the Individual(s) Requesting the Examination
Procedure Date
Adequate Clinical History
Specimen Identification
Specimens Requiring Special Processing
Instructions for the Disposition of Pathology Specimens
References
Chapter 2 Specimen Processing: From Gross Specimens to Tissue Cassettes
General Principles of Processing Specimens
Special Issues in Specimen Processing
General Principles of Gross Descriptions
A Classical Interlude Concerning Terms in Pathology
Selection of Tissue for Microscopic Examination
Fixation
Disposal of Fixatives and Tissues
Disposal of Sharps
Returning Specimens to Patients
References
Chapter 3 The Histology Laboratory—What the Pathologist Needs to Know—From Tissue Cassettes to Glass Slides
Histologic Processing
Possible Misidentification of Tissue
Histological Artifacts
References
Chapter 4 The Surgical Pathology Report: From the Glass Slide to the Final Diagnosis
Elements of a Surgical Pathology Report
Diagnostic Headings
Standardized Reporting
Documenting Paraffin Blocks for Molecular Testing
Turnaround Time
Modification of an Existing Report
Guidelines for Communication of Urgent Results (“Critical Values”)
References
Chapter 5 Special Studies
Histochemistry
Immunohistochemical Studies
Immunofluorescence
DNA Testing
Gene Expression Profiling
Electron Microscopy
Analytical Cytology (Flow Cytometry)
Cytologic Preparations From Surgical Specimens
Specimen Radiography
Infectious Disease—Microbiologic Culture
References
Chapter 6 Occupational Hazards
What Do Pathologists Say about Workplace Safety?
Visual Problems
Musculoskeletal Problems
Injuries And Mucosal Exposures
Chemical Exposures and Radiation
Infectious Disease
Cancer
References
Chapter 7 Microscopy and Photography
Optimal Optics
Oil Immersion Microscopy
Optical Properties
Measuring With the Microscope
Cleaning and Care of the Microscope and Glass Slides
Photography
References
Part Two
Chapter 8 Adrenal Gland
Relevant Clinical History
Processing The Specimen
Special Studies
Gross Differential Diagnosis
Microscopic Sections
Sample Dictation
Pathologic Prognostic/Diagnostic Features Sign-Out Checklist for Adrenal Tumors
Reference
Chapter 9 Amputations and Large Resections
General Gross Description
Traumatic Amputations
Digits—Nontumor
Lower Extremity—Nontumor
Amputations or Large Resections for Tumor
References
Chapter 10 Small Biopsies
Relevant clinical history
Processing the Specimen
Sample dictations
Chapter 11 Bone and Joints
Total Joint Arthroplasty (Hips and Knees)
Core Biopsy For Aseptic (Avascular) Necrosis
Biopsy, Metabolic Bone Disease
Curettings and Needle Biopsies, Bone Tumors
Bone Resections for Tumors
Incidental Ribs
Meniscus
Synovium
Carpal Tunnel Release (Tenosynovium)
Intervertebral Disk Material
References
Chapter 12 Breast
Large Core Needle Biopsies
Incisional Biopsies
Excisions
Global Re-excisions
Shave Margins
Oncoplastic Breast Surgery
Mastectomies for Malignancy
Sentinel Lymph Node Biopsy
Axillary Dissections
Prophylactic Mastectomies
Reduction Mammoplasty
Duct Dissections/Nipple Biopsies
Breast Skin Punch Biopsies
Breast Implants
Gynecomastia
References
Chapter 13 Cardiovascular Specimens
Endomyocardial Biopsies
Native Valves (Aortic, Mitral, Pulmonic, Tricuspid)
Prosthetic Mechanical and Tissue Heart Valves
Ventricular Assist Devices
Heart Explants
Atrial or Ventricular Myocardium
Heart Resections for Tumors
Blood Vessels
References
Chapter 14 Cytology Specimens
Cell Blocks
Storage of Cytology Specimens
Chapter 15 Dermatopathology
Skin Punch Biopsies
Skin Shave Biopsies
SKIN Curettings
Skin Ellipses
Large Skin Excisions
Face Transplants
Lip Excisions
Fingernails and Toenails
References
Chapter 16 Gastrointestinal Specimens
Esophagus
Stomach
Small Intestine
Meckel’s Diverticulum
Colon
Appendix
Hemorrhoids
Liver
Gallbladder
Pancreas
References
Chapter 17 Genitourinary Specimens
Kidney
Sample dictation
Bladder
Ureter
Ureteropelvic Junction
Calculi (Kidney and Bladder)
Prostate
Testis
Retroperitoneal Lymph Node Dissection for Testicular Carcinoma
Testis Sparing Surgery (Partial Orchiectomy)
Bilateral Simple Orchiectomy—Nontumor
Vas Deferens For Sterilization
References
Chapter 18 Gross Examination
Specimens with a Low Yield of Clinically Significant Microscopic Findings
References
Chapter 19 Gynecologic and Perinatal Pathology
Uterus
Ovary
Fallopian Tube
Cervix
Vagina
Vulva
Sentinel Lymph Nodes
Placenta
Products of Conception (POCS)
References
Chapter 20 Head and Neck and Laryngeal Specimens
Sinus Contents
Nasal Polyps
Oral Cavity/Tongue Resections
Neck Dissections (Removal of Lymph Nodes)
Mucosal Biopsies
Salivary Gland
Stapes
Teeth
Tonsils and Adenoids
Larynx
References
Chapter 21 Hernia Sac
References
Chapter 22 Lung and Pleura
Lung
Pleura
References
Chapter 23 Lymph Nodes, Spleen, and Bone Marrow
Bone Marrow
Lymph Nodes
Lymphomas-Extranodal
Spleen-Hematologic Disease
Spleen-Nonhematologic Disease
References
Chapter 24 Medical Devices and Foreign Material
The Safe Medical Devices Act of 1990
Orthopedic Hardware
Radioactive Seeds
Foreign Bodies
Bullets
Releasing Medicolegal Specimens to Law Enforcement
References
Chapter 25 Neuropathology
Brain Biopsies
Biopsies of The Dura
Cavitron Ultrasonic Surgical Aspirator Specimens
Subdural And Subarachnoid Hematoma Evacuations
Brain Resections
Eyes
Lens
Cornea
Nerve Biopsies
Muscle Biopsy
References
Chapter 26 Paraganglioma
References
Chapter 27 Penis
Penis Anatomy
References
Chapter 28 Soft Tissue Tumors (Sarcomas)
Biopsies
Lipomas
Resections
Abdominal Fat Pad Biopsy for the Diagnosis of Amyloidosis
References
Chapter 29 Thymus
Relevant Clinical History
Processing the Specimen
Special Studies
Gross Differential Diagnosis
Microscopic Sections
Sample Dictation
Pathologic Diagnostic/Prognostic Features Sign-Out Checklist For Thymic Lesions
Chapter 30 Thyroid and Parathyroid Glands
Thyroid Resection
Prophylactic Thyroidectomy
Parathyroid Gland
References
Index