Περιγραφή
Non-motor Parkinson’s Disease is a burgeoning area of the movement disorders field, as patients increasingly live longer and encounter more late-stage symptoms. The spectrum of non-motor manifestations spans much of the body, with non-motor features occurring in all stages of the disease. Identification of symptoms is key for preserving quality of life and successful treatment. This is a practical manual on all aspects of pre-motor and non-motor manifestations of Parkinson’s. The genetic causes of non-motor symptoms are detailed and methods of patient evaluation summarized. Topics such as autonomic and sexual dysfunction, mood disorders, and drug-induced symptoms of non-motor Parkinson’s are covered in depth. This is an essential resource for movement disorder specialists, neurologists and other clinicians involved in caring for those with Parkinson’s disease.
- Brings together vital information about non-motor symptoms that has previously only been accessible in disparate sources
- Covers specific symptoms, their pathophysiology, neuroimaging and treatment along with general information on the genetic background of the disease and how to evaluate patients
- A practical manual with advice suitable for all involved in the care of patients with Parkinson’s disease, including movement disorder specialists, neurologists, primary care providers and cardiologists
Περιεχόμενα
Introduction
1. Parkinson’s disease: an overview of non-motor symptomatology Valentina Leta, Daniel van Wamelen and Ray Chaudhuri
2. Evaluation of the patient with Parkinson’s disease in the early stages: non-motor phase Anna Sauerbier, Daniele Urso, Chloe Farrell, K. Ray Chaudhuri and Carmen Rodriguez-Blazquez
3. Non-motor symptoms in late-stage Parkinson’s disease Umar Shuaib, Adam Margolius and Hubert Fernandez
4. Neuropathology of non-motor Parkinson’s disease symptoms Lea Grinberg and Helmut Heinsen
5. Neuroimaging studies in non-motor Parkinson’s disease symptoms David Brooks
6. Mild cognitive impairment Amos D. Korczyn
7. Cognitive dysfunction in Parkinson’s disease Damon Salzman and Shakeel Tabish
8. Neuropsychiatric (behavioral) symptoms in Parkinson’s disease Kasia Rothenberg
9. Mood disorders in patients with Parkinson’s disease Po-Heng Tsai and Ganesh Gopalakrishna
10. Olfactory dysfunction in Parkinson’s disease and related disorders Richard Doty and Christopher Hawkes
11. Oculomotor and visual-vestibular disturbances in Parkinson’s disease Adolfo Bronstein, Aasef Shaikh, Tim Anderson, Michael MacAskill and Diego Kaski
12. Autonomic dysfunction and failure in Parkinson’s disease Thomas Foki, Birgit Riemer, Bianca Brim and Walter Struhal
13. Gastrointestinal disturbances in Parkinson’s disease, including the management of Sialorrhea Wolfgang H. Jost and Lisa Klingelhoefer
14. Sexual dysfunction in Parkinson’s disease Gila Bronner and Tanya Gurevich
15. Sleep disturbances in Parkinson’s disease, including rapid eye movement behavior disorders Cristian Falup-Pecurariu, Ștefania Diaconu and Maria-Lucia Muntean
16. Musculoskeletal disorders and pain in Parkinson’s disease Ovidiu Bajenaru
17. Cutaneous manifestations of Parkinson’s disease Rivka Inzelberg and Esther Azizi
18. Genetics of non-motor symptoms of Parkinson’s disease Ziv Gan-Or, Konstantin Senkevich and Roy Alcalay
19. Drug-induced non-motor symptoms of Parkinson’s disease Camila Aquino
20. Impulse control disorders and the dopamine dysregulation syndrome Atbin Djamshidian, Guillaume Pagnier, Michael J Frank and Joseph H. Friedman
21. Serotonin syndrome and drug interactions, hypertensive complications, and adverse effects of Monoamine oxidase inhibitors in patients with Parkinson’s disease Kailash Bhatia and Eoin Mulroy
22. Parkinson’s disease and pregnancy Shira McMahan, Ramon Lugo-Sanchez and Néstor Gálvez-Jiménez.
