Definition, risk factors, and epidemiology of osteoporosis. Pathogenesis: Molecular mechanisms of osteoporosis. Osteoporosis: Biochemical investigations. Diagnosis: Radiological investigations. Development of a fragility liaison service. NICE guidelines for medical treatment of osteoporosis: An update. Role of bisphosphonates and denosumab. The role of anabolic agents. Current and emerging pharmacological agents in the treatment of osteoporosis. Monitoring/surveillance of medical treatment. Systemic complications of osteoporosis medical treatment. Complications of medical treatment: Atypical fractures. Biomechanical considerations for fixation of osteoporotic bone. The fix and treat principle: An update. Principles of management of osteoporotic fractures. Can we accelerate the osteoporotic bone fracture healing response? Management of osteoporotic proximal humeral fractures: An overview. Distal humerus fractures in the elderly: To fix or to replace? Distal radius osteoporotic features: My preferred method of treatment. Management of osteoporotic pelvic fractures. Management of osteoporotic acetabular fractures: Fix or replace? Management of osteoporotic proximal intertrochanteric/subtrochanteric femoral fractures. Osteoporotic distal femoral fractures: When to fix and how. Osteoporotic distal femoral fractures: When to replace and how. Osteoporotic long bone fractures: My preferred method of treatment. Management of osteoporotic extra-articular proximal tibial fractures. Osteoporotic ankle fractures: Principles of treatment. Treatment of distal intra-articular/extra-articular tibial fractures. Osteoporotic os calcis fractures: How I manage them. Current trend in kyphoplasty for osteoporotic vertebral fractures. Osteoporotic thoracolumbar fractures: My preferred method of nonoperative treatment. Augmentation of fracture fixation: An update. Complications of surgical treatment for osteoporotic fractures. Total shoulder replacement and osteoporosis: An Update. Total hip replacement and osteoporosis: Current trends. Total knee replacement and osteoporosis: An overview. Rehabilitation of the osteoporotic patient: Is it different?