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Zebrafish as a Model for Parkinson’s Disease

ISBN: 9781032515779
ISBN: 9781032515779
Εκδόσεις:
Διαστάσεις 30 × 21 cm
Μορφή

Hardcover

Εκδόσεις

Ημ. Έκδοσης

2024/09

Σελίδες

320

Έκδοση

1η έκδοση

Κύριος Συγγραφέας

210,00€(Περιλαμβάνεται ΦΠΑ 6%)

Διαθεσιμότητα: Υπό έκδοση

Περιγραφή

The increasing demand for innovative techniques arises from the lack of safe, effective, and patient-friendly therapies for neurodegenerative disorders. With this objective in mind, the chapters of the book are structured to offer a thorough insight into recent advancements in utilizing the Zebrafish (ZF) as a model for studying Parkinson’s disease (PD). This book aims to present readers with a comprehensive understanding of the clinical application of the ZF model in treating PD, encompassing the latest developments, challenges, safety considerations, toxicity issues, regulatory aspects, future potential, and limitations. Individuals in academia, the scientific community, business, and education seeking a more effective approach to target the brain stand to benefit from this resource.

Key Features

· Provides a comparative perspective of the Zebrafish-Parkinson’s Disease model

· Highlights the restrictions of available medicines

· Describes biochemical and histopathological characteristics, advantages and disadvantages of this model

· Emphasizes distinct facets of histopathology

· Presents advances and developments of the future potential perspectives

Περιεχόμενα

SECTION-I: FROM AQUARIUM TO LAB: THE RISE OF ZEBRAFISH AS A MODEL ORGANISM

 

Ch1 General Methods For Zebrafish Care

Fatemeh Delkhosh Kasmaie, Yaser Tahamtani, Mohammad Rezaei

 

Ch2 Breeding of Zebrafish and its life cycle

Hakim Mudasir Maqsood1, Inain Jaias, Asra Imtiyaz Mattoo, Towseef Akram, Wasim Akram5, Nazir Ahmad Ganai

 

Ch3 Neurobehavioral assessment of Zebrafish

Shaimaa Nasr Amin, Dalia Azmy Elberry

 

Ch4 Cellular and Genetic Methods in Zebrafish

Dalia Hamza, Elshaimaa Ismael, Hala Zaher

 

Ch5 Repeated blood sampling from an adult Danio rerio

Manar A. Eissa, Raihan Abdullah, Faez Sharif, Mohd Hamzah Mohd Nasir

 

Ch6 Zebrafish Culture

 Zahra Morshed1, Fatemeh Delkhosh Kasmaie, Mahsa Valizade, Mohammad Rezaei, Yaser Tahamtani

 

Ch7 Calcium Imaging of Neuronal Activity in Free-Swimming

Larval Zebrafish

Rui Peng, Xiuyun Liu, Meijun Pang

 

Ch8 Anesthesia, Analgesia, and Euthanasia of the Laboratory Zebrafish

Azhwar Raghunath

 

Ch9 Zebrafish Guidelines, Policies and Regulations in Research

Yashwanth Bomma, Rajesh Pamanji, Joseph Selvin

 

SECTION-II:  ZEBRAFISH AS A MODEL OF PARKINSON’S DISEASE

 

Ch10 The Role of Neurotransmitters in the Pathophysiology of Parkinson’s Disease

Shaimaa Nasr Amin , Dalia Azmy Elberry

 

Ch11 Diagnosis and Biomarkers of PD

Abraham Olufemi Asuku, Maryam Tayo Ayinla, Olajide Tobiloba Samuel, Ebele Joan Ajagun, Kaosara Oyinola Ganiyu, Yusuf Olamilekan Hamza, Ayodeji Johnson Ajibare, Taoheed Adedeji Abdulsalam

 

Ch12 Parkinson’s Disease Models Pros and Cons

Sobhana M, Rajesh Pamanji, Joseph Selvin

 

Ch13 Pharmacotherapy of PD and their limitations

Ebele Joan Ajagun, Abraham Olufemi Asuku1,Maryam Tayo Ayinla, Taoheed Adedeji Abdulsalam, Ayodeji Johnson Ajibare, Olajide Tobiloba Samuel, Yusuf Olamilekan Hamza, Kaosara Oyinola Ganiyu

 

Ch14 Induction and VALIDATION OF ZF model of PD

Gisha Sivan, Rajesh Pamanji, Joseph Selvin

 

Ch15 Zebra fish as a model for a novel Parkinson’s disease protective natural Product

Hagar F. Forsan

 

Ch16 Zebrafish model for studying microbiome associated Parkinson’s Disease

Vishnu Prasad Nair R U, Rajesh Pamanji, Joseph Selvin

 

Ch17 Transgenic zebrafish reporter lines for in vivo studying of Parkinson’s disease

Nicola Facchinello

 

Ch18 Interplay of neurodenegrative disorders in zebrafish:  unlocking the mystery

Sanobar Shariff , Burhan Kantawala, Qamar Sultana, Hasiba Karimi, Ider Oujamaa, Vivek Sanker

 

Ch19 Smart Capsule and Edible Bird’s Nest: Charting New Frontiers in Parkinson’s Disease Defense-An Experimental Protocol Perspective

Wael MY Mohamed

 

Ch20   Zebrafish Model for Drug Discovery and Screening

Sarah Hassan, Jabra Mustafa, Ahmad Hassan, Wael Mohamed