Precision medicine holds great promise for the treatment of cancer and represents a unique opportunity for accelerated development and application of novel and repurposed therapeutic approaches. Current studies and clinical trials demonstrate the benefits of genomic profiling for patients whose cancer is driven by specific, targetable alterations. However, precision oncologists continue to be challenged by […]
This book provides an update on recent clinical practice and an in-depth view of selected topics relevant to hospital medicine. It is divided into four sections that explore clinical, administrative, systems and ethical issues. Each section places an emphasis on the opportunities, challenges and potential directions of this bourgeoning subspecialty. This new edition expands on […]
Keeping up to date with advances in comprehensive ophthalmology and in the ophthalmic sub-specialties is extremely difficult because of the accelerating rapidity with which new information and technology become available and the diminishing time and opportunity for practitioners and trainees to read and learn. The first edition of Albert and Jakobiec’s Principles and Practice (1994) was conceived […]
This revised and updated edition reflects the increasing popularity of noninvasive techniques in the management of vascular disease. It represents the definitive text written on the subject and has been honed over the past editions to represent the enormous number of changes to the use of imaging to diagnose the multitude of conditions being seen […]
This book, now in its third, completely revised and updated edition, offers a critical approach to the challenging interpretation of the latest research data obtained using functional neuroimaging in whiplash injury. Such a comprehensive guide to recent and current international research in the field is more necessary than ever, given that the confusion regarding the […]
This book discusses the evidence behind the relationship between COVID-19 and heart disease based on emerging state-of-the-art data. The rapid and unexpected global spread of the COVID-19 has revealed proportional levels of cardiovascular and metabolic complications. A myriad of pathogenetic mechanisms has come to the surface. There is still much research required to define whether […]
This book provides a structured and analytical guide to the use of artificial intelligence in medicine. Covering all areas within medicine, the chapters give a systemic review of the history, scientific foundations, present advances, potential trends, and future challenges of artificial intelligence within a healthcare setting. Artificial Intelligence in Medicine aims to give readers the […]
This book provides a practically applicable guide to the use of ultrasound in the care of acutely and critically ill patients. It is laid out in two sections. The first section attempts to take a comprehensive approach to specific systems of examination taking an organ focused approach covering techniques including Focussed Assessment with Sonography for […]
Par-4 is a tumor suppressor protein first discovered and identified in 1993 by Dr. Vivek Rangnekar’s laboratory in prostate cancer cells undergoing apoptosis. Par-4 (later also known as PAWR) is a naturally occurring tumor suppressor. Studies have indicated that Par-4 selectively induces apoptosis in cancer cells while leaving normal, healthy, cells unaffected. Mechanisms contributing to […]
This fully updated and expanded third edition is a reference guide on nutrition and its clinical implications for health and disease through the life-cycle. The book endeavors to address the needs of those who would most benefit from up-to-date information on recent advances in the field of nutrition. Written by experts in the field, chapters […]
This comprehensive textbook provides physicians with a practical evidence-based framework to evaluate and manage patients suspected of having overlap disorders involving the integumentary, musculoskeletal and related systems. The book discusses hallmark mucocutaneous features which support, and often specify, diagnosis, and it provides a summary of relevant multisystem examinations, serologic workup, and imaging. Interdisciplinary perspectives on […]
The authoritative textbook on the principles and practical applications of biopharmaceutics and pharmacokinetics Shargel & Yu’s Applied Biopharmaceutics & Pharmacokinetics has been the standard textbook in its field for over 40 years. This eighth edition includes recent scientific developments in the field and embodies the collective contribution of experts with deep knowledge and experience in […]
Our knowledge of cerebellar functions and cerebellar disorders, called ataxias, is increasing considerably. Studies of the cerebellum are now a central focus in neuroscience. During the last four decades, many laboratories worldwide have dedicated their research activities to understanding the roles of the cerebellum in motor control, cognitive processes and biology of mental processes, behavioral […]
‘Skull Base Surgery’ represents genuinely multi-disciplinary collaborative approach to the standard procedures in skull base surgery. It emphasizes the basic operative steps of each approach and describes variations from the basic approach. Authors from the relevant specialties Neurosurgery, Otolaryngology, Maxillo-Facial Surgery and Plastic Surgery contribute to this new specialty of skull base surgery.
This unique book is the first to focus on diagnostic and therapeutic endoscopy in gastrointestinal and pancreatico-biliary diseases. It provides an in-depth overview of the state of the art in diagnostic and therapeutic endoscopy of both the digestive tract and the pancreatico-biliary ductal system, and documents the latest innovations in the field. The first part […]
This book provides an accessible, up-to-date understanding of how to treat patients with substance and non-substance-related addiction. It covers all the typical substance and non-substance use disorders and presents evidence in a case-based format. Concise and comprehensive, opening chapters relay a preliminary assessment of addiction disorders and their neurobiology. Subsequent chapters then offer specific treatment […]
This book provides a comprehensive resource for clinical hepatology. It details the systematic approach to patients with liver disease in outpatient and inpatient medical settings. A variety of case studies in hepatology including chronic viral hepatitis, and metabolic, autoimmune, and alcohol related liver disease are presented. The book enables the reader to develop a thorough […]
This book features in-depth descriptions of imaging modalities (MRI, CT, US, PET) for all orbital pathologies, including tumors, vascular anomalies, congenital anomalies, trauma, inflammations and infections. It describes all the imaging features of the pathologies, and includes guidance for differential diagnosis and relevant clinical data. Atlas of Orbital Imaging serves as a clinical and educational resource for […]
Bringing together thousands of the best dermatologic clinical and pathological photographs and figures from researchers and scientists around the world, this volume focuses on the most prevalent dermatologic disorders as they relate to inflammatory dermatoses. This volume includes atypical presentations of various disorders, giving insight into differential diagnoses, helping to familiarize the reader with some […]
Bringing together thousands of the best dermatologic clinical and pathological photographs and figures from researchers and scientists around the world, this volume focuses on the most prevalent dermatologic disorders as they relate to cutaneous anatomy, general dermatologic concepts, and biology and inherited disorders. It includes atypical presentations of various disorders, giving insight into differential diagnoses, helping to […]